ABSTRACT
Da Jianzhongtang， which is from Synopsis of Golden Chamber（《金匮要略》）， is one of the hundred ancient classical formulas. In this textual research， a total of 46 records on this prescription from 42 ancient books and 207 records from modern literature were screened out. Through systematic research on its name， dosage， processing， evolution of the meaning on prescription compatibility， indications， decocting methods， usage， and precautions， this paper aims to lay a literature basis for further research on Da Jianzhongtang. The results show that the converted dosages for the components are 3 g of Zanthoxyli Pericarpium， 12 g of Zingiberis Rhizoma， 6 g of Ginseng Radix et Rhizoma， and 30 g of Saccharum Granorum. The efficacy can be labeled on the prescription instruction as warming the middle and tonifying deficiency， descending adverse Qi and relieving pain. According to modern literature， the main indications include diseases in digestive system， circulatory system， orthopedic system， urinary system， and ophthalmic system， particularly the intestinal obstruction， gastric ulcer， chronic gastritis， and duodenal ulcer in the digestive system. The core pathogenesis of the above diseases is "deficiency-cold of middle energizer and internal exuberant cold". Precautions are as follows. ① For the processing of Zanthoxyli Pericarpium， stir-frying can alleviate its toxicity and increase the decoction rate of effective ingredients. ② For the dosage， overdosage will lead to dry cough， edema， etc. ③ As to the contraindications after the medication， raw， cold， or indigestible food should not be taken after medication. ④ For the syndrome taboos， this prescription should be used with caution for patents with Yin deficiency， congealing cold， and Qi stagnation， and be forbidden for patients with spleen and stomach dampness-heat. The above results lay a basis for the research and development of the compound preparation for Da Janzhongtang and provide a reference for its instructions.
ABSTRACT
Objective To observe the sealing effect of transient pinus massoniana bark extract (PMBE)pre-coating on dentin tubules and its wear resistance so as to provide an experimental basis for PMBE to be used to prevent and treat dentin hypersensitivity.Methods The model of dentin hypersensitivity was established by acid etching method.The samples were transient pre-coating with 80 g/L of PMBE ethanol solution,and then some of them experienced brushing wear treatment with ethanol group and fluorine vanish group as negative and positive controls.The surface and profile morphologies of the samples were observed using field emission scanning electron microscope (FESEM)in each group.The area of dentin tubular openings (ADTO)and percentage area of dentin tubular openings (PADTO)were also measured.Results The dentin tubules were opened completely and the lumen of dentin tubules was empty in ethanol group.The dentin tubules were completely or basically closed and some films or plugging could be seen in the lumen of dentin tubules in fluorine vanish/immediate group and PMBE/immediate group.The dentin tubules were partly opened and some wear marks could be seen on the dentin surface in fluorine vanish/wear groups,PMBE/wear groups.ADTO and PADTO in ethanol group were significantly higher than those in fluorine vanish groups and PMBE groups (P＜0.05).ADTO and PADTO did not significantly differ between fluorine vanish/wear groups and PMBE/wear groups (P＞0.05),which were all significantly higher than those in fluorine vanish/immediate group and PMBE/immediate group (P＜0.05).Conclusion Local transient pre-coating of PMBE ethanol solution can achieve fine immediate sealing effect of dentin tubules and some degree of wear resistance.
ABSTRACT
<p><b>OBJECTIVE</b>To observe the therapeutic effect of fire-needle therapy on lumbar intervertebral disc herniation.</p><p><b>METHODS</b>Sixty cases were randomly divided into a fire-needle group and an electroacupuncture group, 30 cases in each group. The fire-needle group was treated with fire-needle therapy and routine acupuncture, i.e., the fire-needle was given to the points on the lesion segments, and Jiaji (EX-B 2) and Ashi points above and bellow the segments, and routine acupuncture was given at Shenshu (BL 23), Zhibian (BL 54), Huantiao (GB 30), etc.; the electroacupuncture group was treated with electroacupuncture at the points as those in the fire-needle group. The scores of McGill Pain Rating Scale, Visual Analogous Scale (VAS) and present pain intensity (PPI) were compared before and after treatment for 2 weeks in the two groups.</p><p><b>RESULTS</b>After treatment, all of the scores of McGill Pain Rating Scale, VAS and PPI were significantly decreased (all P < 0.01); the scores of emotion in the McGill Pain Rating Scale, VAS and PPI in the fire-needle group were significantly decreased as compared with those of the electroacupuncture group (P < 0.05, P < 0.01).</p><p><b>CONCLUSION</b>Both fire-needle therapy and electroacupuncture can effectively relieve pain in the patients with lumbar intervertebral disc herniation, but the former is better than the latter.</p>