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AIM: To investigate the refractive distribution and analysis risk factors for aircrew ametropia. METHODS: The number of 49 cases with ametropia from 1031 aircrew during May 2013 to May 2014 were reviewed. Various types of refraction composition, age, type, position, time of flight with the subjective assessment of aircrew were analyzed and compared. RESULTS:Of 49 cases, 43 cases (88%) were myopia, 6 cases ( 12%) were hypermetropia. , Detection rates were higher in age over 50 years aircrew and flight time more than 3000h. Detection rates were lower in self-conscious symptom heavy aircrew, fighter aircrew and good habit of using eyes. CONCLUSION: The myopia incidence in aircrew with age >50 years and long flight time is higher, than that of fighter pilots and good habit of using eyes. We should pay attention to the increasing late-onset myopia of aviators and habit of using eyes, work intensity and time of using eyes about aircrew.
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Fingerprint technology is the key technology in modern Chinese medicine research, while spectrum-effect relationship research is the advanced stage of fingerprint research. Spectrum-effect relationship research can reveal the relationship between fingerprint and pharmacological effect through multiple statistical analyses, which can be used in Chinese medicine research. Spectrum-effect relationship has been used in many areas of Chinese medicine research, such as effective basis of single and compound Chinese medicine research, component compatibility research, processing mechanism research, pharmacological effect forecast research, technology optimization research, and so on. This paper systematically reviewed the application of spectrum-effect relationship in Chinese medicine research, and indicated some problems in spectrum-effect relationship research. At last, the authors give an outlook of the future of spectrum-effect relationship research.
Subject(s)
Animals , Humans , Biomedical Research , China , Drugs, Chinese Herbal , Chemistry , Pharmacology , Spectrum AnalysisABSTRACT
Baizhu Shaoyao San is a famous traditional Chinese medicine formula, which is efficient to diarrhea clinically. However, there are very few reports for extraction process of Baizhu Shaoyao San at present. In this article, an orthogonal test was conducted, with 10 major components and extractum of Baizhu Shaoyao San as indexes, and data was processed by the compound weight method, in order to detect four factors, including the concentration of ethanol, the dosage of ethanol, the soaking and extracting times, and optimize the extraction process of Baizhu Shaoyao San. The results showed that the optimal extraction process was adding 12-fold ethanol of 70% concentration, soaking for 1 hours, and extracting for twice, 2 hours each time. Among the indexes, the extracting time made significant impact. The optimized method is stable and reliable, and can provide reference for further development and utilization of the formula.
Subject(s)
Chemical Fractionation , Methods , Chromatography, High Pressure Liquid , Drugs, Chinese Herbal , Plants, Medicinal , ChemistryABSTRACT
The purpose of this study was to evaluate the effect of preoperative inhalation of milrinone on cardiopulmonary bypass [CPB]-related inflammation. A total of 30 patients undergoing cardiac surgery were recruited and randomized for preoperative inhalation of milrinone [Mil group] or normal saline [NS group], respectively. Each group had 15 patients. Their hemodynamic parameters were measured and blood samples were obtained longitudinally. The levels of serum interleukin [IL-6], tumor necrosis factor-alpha [TNF-alpha], and matrix metalloproteinase [MMP]-9 were determined by ELISA. The levels of serum IL-6, TNF-alpha, and MMP-9 significantly increased at the end of cardiac surgery and remained high for 24 h in both groups of patients. However, the levels of proinflammatory cytokines at the end of cardiac surgery in the Mil group of patients were significantly lower than those of the NS group of patients. Our data indicated that preoperative inhalation of milrinone significantly mitigated CPB-related inflammation
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This paper introduce the professor WU Lian-zhong's clinical experience in acupuncture treatment for facial paralysis. Professor WU emphasizes the treatment based on syndrome differentiation. The appropriate theory, method, prescription and acupoints should be applied according to observing the subtle details of syndromes and differentiating the state of diseases development, so as to obtain effectiveness, to shorten the duration of treatment course and to reduce sequelae. The concrete methods of prognosis diagnosis for facial paralysis and three effective cases are introduced.