ABSTRACT
Objective To explore the application of washing fluid in the prevention of postoperative incision infection of colorectal cancer. Methods 350 patients with colorectal cancer underwent colorectal surgery from Jan. 2012 to Dec. 2015 were randomly divided into three groups: sterile saline, 0.50% metronidazole, 0.50% Povidone-iodine solution group, while part of the rinse liquid heated to 37 ~38℃ before use, then record the operation time, surgical site, postoperative incision infection, incision infection, timely delivery statistical analysis was performed by using single factor analysis and logistic multivariate regression analysis. Age, operation time, surgical site, type of irrigating fluid and temperature of flushing fluid were analyzed statistically. Results The incision infection rate of the patients ≥60 years old and the operation time ≥2 h was higher than the age <60 years, and the operation time was less than 2 h, P < 0.05, the difference was statistically significant; 0.50% metronidazole, 0.50% Povidone-iodine solution group, the infection rates of 0.50% metronidazole and 0.50% povidone-iodine group were 7.69% and 8.55%, respectively, which were significantly lower than those of the saline group 16.38% The infection rate of the rinsing fluid after heating was 7.22% and 14.71%, respectively, lower than that of the normal temperature rinsing solution (P < 0.05), the difference was statistically significant. Conclusions The risk factors of incisional infection in colorectal cancer patients with colorectal cancer were : ≥60 years of age and ≥2 h of operation, while 0.50%metronidazole, 0.50% povidone-iodine solution and heated washing fluid were protective factors. It can be applied to prevent incision infection after laparoscopic surgery.
ABSTRACT
Objective To explore the feasibility and effectiveness of the interspincterotomy combined with PPH in the treatment of severe mixed hemorrhoids and anal fissure.Methods 116 cases of glioma patients with post-operative residual lesions were treated.The observation group of 58 patients were treated with internal sphincterotomy combined with PPH resection,while 58 cases in the control group were treated by traditional external dissection and internal ligation plus resection of anal fissure.The efficacy and safety of treatment of the two groups of patients were evaluated.Results The operation time,hospitalization time,healing time,postoperative curative effect evaluation score of the observation group were (22.5 ±5.3)min,(2.1 ±0.9)d,(9.6 ±2.1)d and (9.8 ±1.6)points,respec-tively,which of the control group were (35.2 ±6.7)min,(9.1 ±2.5)d,(18.4 ±3.7)d and (5.3 ±1.2)points, there were significant differences between the two groups(t =5.68,4.95,6.33,1.35,all P 0.05),but seventh days after the operation,the pain,edema,hemorrhage control scores of the observation group were significantly better those of the control group(all P <0.05).The complication rate of the observation group was 5.17%,which of the control group was 17.24%,there was significant difference between the two groups(χ2 =4.25, P <0.05).Conclusion The interspincterotomy combined with PPH is an operation that meeting the requirements of modern hemorrhoid treatment.It is a safe and effective treatment.It is worthy of further promotion in the treatment of severe mixed hemorrhoid and anal fissure.