ABSTRACT
OBJECTI VE: To observe the long termtherapeutic effect of compound glycyrrhizinin treating active cirrhosisfollowing chronic hepatitis B.METHODS:58patients with active cirrhosis received compound glycyrrhizin60ml intra-venously once a day for18consecutive months.The changes in clinical symptoms,signs,biochemical indicators,virologyindices after treat ment were observed.RESULTS:35cases of active cirrhosis remained stable after treat ment,ascites disap-pearedin5cases,and17patients returnedto work.The quantitated decreasein HBV-DNA was greater than103copies/ml,HBeAg negative rates reached33.3%.CONCLUSION:Long-termtreat ment with compound glycyrrhizin for active cirrhosisfollowing hepatitis B cani mprove liver function,prevent the worsening of patients’condition,andi mprove life quality.