ABSTRACT
Venous thromboembolism (VTE) is one of the common complications of lung adenocarci-noma. The state of the driver genes of lung adenocarcinoma is related to the risk of VTE. The common driver genes include epidermal growth factor receptor, anaplastic lymphoma kinase, c-ros oncogene 1 receptor kinase and Kirsten rat sarcoma viral oncogene, etc.. Based on the study of the correlation between lung adenocarci-noma driver genes and VTE, it is of great significance for the early clinical prevention of VTE in patients with lung adenocarcinoma to screen out patients with high risk of VTE according to the state of the driver genes and finally evaluate the risk of VTE in patients with lung adenocarcinoma by combining conventional risk factors with the driver genes.
ABSTRACT
Objective@#To investigate the current status of job burnout in in-service sailors, and to provide a basis for the development of intervention measures for job burnout in sailors.@*Methods@#From September 2015 to May 2016, stratified cluster random sampling was used to select 6 172 in-service sailors from 13 provinces and cities as research subjects. General demographic data including age, education background, and household registration and occupational characteristics such as job position, navigating zone, and nature of employment were collected. The Maslach Burnout Inventory-General Survey (MBI-GS) was used to measure the levels of emotional exhaustion, depersonalization, low occupational efficiency, and job burnout, and the influencing factors for job burnout were also analyzed.@*Results@#Of all 6 172 in-service sailors, 112 (1.8%) had a positive result in emotional exhaustion, 870 (14.1%) had a positive result in depersonalization, and 3 517 (57.0%) had a positive result in low occupational efficiency. Of all sailors, 63.3% had job burnout, among whom 54.1% had mild burnout, 8.7% had moderate burnout, and 0.5% had severe burnout. There was a significant difference in the score of job burnout between the sailors with different ages, education backgrounds, types of household registration, job positions, navigating zones, ornature of employment (P<0.05). Age, education background, household registration, job position, navigating zone, and nature of employment were major influencing factors for job burnout in in-service sailors (P<0.05) , and there was a higher level of job burnout in the sailors with an age of 30-39 years, education background of junior college or above, urban registration, a job position of second mate/third engineer, a navigating zone of coastal lines, orthe nature of employment of freelance sailor.@*Conclusion@#There is a high incidence rate of job burnout among in-service sailors, and the sailors with a young age, urban registration, a navigating zone of coastal lines, or thenature of employment of freelance sailor tend to have low occupational efficiency. Related measures should be adopted for active intervention.
ABSTRACT
OBJECTIVE: To develop a mental health self-assessment scale for Chinese seafarers. METHODS: The detail dimensions and clauses of Mental health scale for Chinese seafarers( MHSCS) was composed through literature reviews,interviews and expert evaluation. A total of 1309 seafarers were randomly recruited as test subjects by convenience sampling method, and the preliminary scale was constructed to predict their mental health. The formal scale was established after data analysis by analyzing means of differentiation,correlation,exploratory factor and frequency,then its reliability and validity were tested. RESULTS: The MHSCS contains 109 entries in 11 dimensions. Its Cronbach 's αcoefficient of the total scale and each dimension was 0. 638-0. 982,and the retest reliability was 0. 806-0. 922. The scores in each dimension of the scale were positively correlated with the scores of each dimension of Symptom Checklist 90 scores( correlation coefficient = 0. 486-0. 860,P < 0. 01). The confirmatory factor analysis showed that the model fitted well(x~2/df = 2. 93,the normed fit index was 0. 950,the non-normed fit index was 0. 970,the incremental fit index was 0. 970,the relative fit index was 0. 950,the comparative fit index was 0. 970,the root mean square error of approximation was 0. 067). CONCLUSION: The MHSCS has good reliability and validity,meets the requirements of psychometrics standard,and can be used as a mental health evaluation tool for the Chinese seafarers.