ABSTRACT
The alkaloids of Daphniphyllum angustifolium were investigated. The whole plant was extracted with 95% EtOH, six alkaloids were isolated and purified with column chromatography over silica gel, RP-18 and Sephadex LH-20. Based on spectral analysis, their structures were identified as daphnilactone B (1), zwitterionic alkaloid (2), yuzurine (3), dehydrodaphnigracilline (4), deoxyyuzurimine (5) and macrodaphniphyllidine (6). All of compounds were obtained from the plant for the first time.
Subject(s)
Alkaloids , Drugs, Chinese Herbal , Magnoliopsida , Chemistry , Plant Leaves , ChemistryABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents of involatile moiety of Pogostemon cablin.</p><p><b>METHOD</b>Compounds were isolated and purified by repeated column chromatography, and their structures were elucidated by spectroscopic analysis.</p><p><b>RESULT</b>Nine compounds have been isolated and identified: epifriedelinol (1), 5-hydroxymethol-2-furfural (2), succinic acid (3), beta-sitosterol (4), daucosterol (5), crenatoside (6), 3'''-O-methylcrenatoside (7), isocrenatoside (8), and apigenin-7-O-beta-D-(6"-p-coumaryl)-glucoside (9).</p><p><b>CONCLUSION</b>Compounds 2, 3, 6-8 were isolated from Pogostemon genus for the first time.</p>