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Objective:To evaluate the performance of Sysmex company's new product Sysmex XN-9000 automatic blood fluid analyzer and confirm the test results. Methods: According to the American association of clinical laboratory standardization guidelines EP15-A2, the EP6-A2 requirements for Sysmex XN-9000 blood analyzer for precision, carry pollution rate, linear range and accuracy verification, to Backman LH750 comparison results for evaluating the basis, the results and the performance of manufacturer's statement or recognized quality standards. Results:XN-9000 blood analyzer determination of white blood cell (WBC), red blood cell (RBC), hemoglobin (HGB), RBC deposited (HCT) and platelet (PLT) the main parameters in the batch coefficient of variation (CV%) of 0.11%~0.11%, between the group of CV% of 0.12%~0.12%, linear correlation r is 0.99991~0.99999, carry pollution rate was 0.00%~0.38%, the correlation analysis of each index r>0.999, the indicators accuracy verification bias of 0.67~0.67. Conclusion: XN-9000 instrument for determination of main parameters of precision, accuracy, linear, carrying pollution rate and other major evaluation indexes meet the requirements, test results can be used for clinical diagnosis and treatment of related diseases and curative effect judgment.
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BACKGROUND: Nervousness, anxiety and depression are important inducing factors of migraine, while nervousness, anxiety and depression are closely correlated with the unreasonable belief and incorrect strategy. Medicine therapy is the principal method in the treatment of migraine at present, but it cannot change the unreasonable belief of the patients and thereby to reducethe occurrence of the inducing factors of headache.OBJECTIVE: To observe the near term and long term therapeutic effects of medicine therapy and rational emotional behavior therapy(REBT) to provide a safer and more effective intervention for the patients with migraine and thereby to improve their long term quality of life(QOL).DESIGN: An observatory comparative study based on patients with migraine as subjects and healthy population as controls.SETTING: A psychological consultation clinic of a municipal hospital(has been canceled now).PARTICIPANTS: Totally 86 cases of migraine including 34 males and 52females aged between 16 and 48 years old(means of 35 years old) with a course of disease between 2 and 11 years were selected from the Psychological Consultation Clinic of the 289 Hospital between March 1999 and October 2001. All 86 cases were randomly divided into REBT group and medicine group with 43 cases each. There was no significant difference of age, gender,course of the disease, situation of the disease, and education background between two groups. Another 30 healthy individuals including 12 males and 18 females with a mean age of 36 years old were selected in control group.METHODS: REBT was applied for patients in REBT group. Patients of medicine group received 50-100 mg/day of Amitriptyline and 60 mg/day of nimodipine through oral administration. Patients received 12 weeks of therapy followed by 24 weeks of observation.MAIN OUTCOME MEASURES: Therapeutic scale score on migraine (TSSM), before and after migraine-correlated potential(P300) and symptoms checklist 90 (SCL-90) scores were compared.RESULTS: SCL-90 total points of two groups of patients were significantly higher than that of control group( P ＜ 0.05); after 12 weeks of therapy,TSSM, SCL-90 total points and points of major factors of two groups of patients were significantly lower compared with the situations before therapy( P ＜ 0.05), but there was no significant difference between two therapy groups; on the 12th week after therapy, SCL-90 total points, points for major factors and TSSM, and P300 latency of REBT group were almost as the same as that after 12 weeks of therapy and the wave amplitude of P300 significantly elevated; owever, the differences in SCL-90 total points, points of major factors, and the TSSM in medicine group were significant compared with that after 12 weeks of therapy( P ＜ 0.05) . There was significant difference at the same period between two therapy groups ( P ＜ 0.05).CONCLUSION: REBT can reduce the attacks of migraine, decrease TSSM,and has similar therapeutic effects to medicine group. Simultaneously, it can ameliorate the cognitive disorder, change the unreasonable belief of the patients, and improve the strategy to cope with the disease; hence its long term therapeutic effect is better than medicine therapy.
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Objective: To observe the effect of Deanxit and Nimodipine on the headache of anxiety and depression neurosis. Methods:Fifty anxiety and depressive neurosis patients with headache were randomly divide into groups A and B. Group A: Daenxit and nimodipine therapy,group B: Deanxit therapy. All the patients were examined in TCD, Hamilton Anxiety Scale, Hamilton Depression Scale (HAMH、HAMD)and the chief symptom changes before and after therapy. Results: Eight weeks after therapy, the cerebral blood fluid in group A was improved,but it was insignificant in group B. The symptoms of anxiety,depression and headache in group A were much better improved than that of group B. Conclusion: Deaxit had a better anti-anxiety and antidepression function. Nimodipine could improve markedly headache less for anxiety and depression. It was more effect that synthetic therapy than single anti-anxiety and antidepression.