ABSTRACT
Objective To investigate the early change of the function of hemostasis and coagulation as well as clinical significance in the full-term newborns recoveried from stifle.Methods To detect the platelet count (PLT),prothrombin time,fibrinogen and D-dimer in early stage of 50 newborns with different degrees of asphyxia recovreied from stifle,and compared with the control group.Results Compared with the control group,there were not obvious change in PLT in asphyxiated full-term newborns(P>0.05),and the differences of prothrombin time,D-dimer and fibrinogen were statistically significant(P<0.01),the more serious degree of asphyxia,the lower of the fibrinogen and higer of the D-dimer.Conclusions The function of hemostasis and coagulation can be changed in early stage of newborns recoveried from stifle.The detection of fibrinogen and D-dimer in early stage of newborns recovefied from stifle has important clinica significance.
ABSTRACT
Objective To explore the relationship between serum levels of leptin and the physieal development and the infuences of diseases on the levels of leptin in prematurities.Methods To collect the clinical data as well as weights,lengths of 40 sick premature infants(sick group)and 30 premature infants without sick diseases(control group)and to test the serum levels of leptin using radioimmunoassay(RIA)at 1d,7d and 12d of life,and to analyze the differences of serum levels of leptin and weights,lengths and body mass index(BMI)between two groups.Results In both groups the BMI and the serum levels of leptin were decreased at d7 of life and reincreased at d12 of life(P＜0.01),and the serum leptin levels were corresponding to the changes of the physical development of premature infants at ld,7d and 12d of life(P＜0.01).The serum leptin levels were lower in sick group compared with control group at 7d and 12d of life(P＜0.05).Conclusion It suggested that there was positive correlation between serum leptin level and the physieal development in prematurities and diseases had negative influences to the leptin levels.