ABSTRACT
Objective To investigate protective of umbilical cord-mesenchymal stem cells ( UC-MSC ) on idiopathic pulmonary fibrosis ( IPF ) experimental mode was induced by bleomycin in mice .Methods IPF experimental mode induced by bleomycin with intratracheal injection , and then the fourth generation UC-MSC was injected in caudal vein.The lung tissues were obtained to evaluate the influence of UC-MSC on IPF by the observation of histological evaluation(HE) and Masson staining, the detection content of hydroxyprine(HYP), superoxyde dismutase(SOD) and malonaldehyde ( MDA) .Results The HE and Masson staining showed that bleomycin +UC-MSC group could alleviate inflammatory cell infiltration and pulmonary interstitial collagen deposition.bleomycin+UC-MSC group could decline the content of HYP(P<0.01), MDA(P<0.05) and improve the content of SOD(P<0.01)compared with bleomycin group.Conclusion UC-MSC exhibits an protective effect on IPF experimental mode induced by bleomycin in mice.
ABSTRACT
Objective To discuss the practice of nursing management model of stroke unit based upon the international standards implemented in the neurological unit.Methods The experiences of the stroke unit management were summarized and applied to instruct the clinical practice.Results After the implementation,the average hospitalization days,the proportion of drugs,medical cost,and mortality rate decreased.The satisfactory degree of patients with the stroke unit increased.Conclusions The nursing management model of stroke unit not only improved the quality of nursing service to stroke patients,but also decreases the mortality and disability rate,shortened the length of hospital stay,and enhanced the satisfaction degree of patients and their family members.
ABSTRACT
Objective To study the effects of sucking sputum with face upwards and neck raised in order to supply a new method for sputmn sucking.Methods One hundred and twenty-three patients were randomly divided into the experimental group(n=61)and the control group(n-62).The experimental group adopted modified mode:cleaned up the sputum within the mouth and nasal cavities with the traditional manner firstly,then the patients lay down,the nurses raised the patients'neck softly with one hand,removing the pillows,while putting the hypothenar of the other one on his forehead,kept the airway open to suck sputum.The control group adopted common mode,but using the modified method when the common mode failed.Results There was significant difference in phlegm sucking effect between the two groups(P＜0.01).Besides,the first-time success rate d tube insertion,incidence of trachcotomy,mucosal injury and hemorrhage and satisfaction degree of patients'family were statistically different between the two groups(P＜0.01).Conclusion Sucking sputum with face upwards and neck raised waS superior to the traditional one.