ABSTRACT
A small circuit system of anesthesia was developed by Fonseca and Goldenberg in 1993. The authors used in this study New Zealand White (NZW) rabbits under closed system anesthetic regiment by isoflurane. Twenty male adult New Zealand rabbits were distributed in two groups of tem animals. No premedicant drugs were given. Endotraqueal intubation was made after intravenous administrations of propofol (10 mg/kg). Isoflurane was used to anesthesia management, administrated by lowflow closed system technique with copper kettle vaporizer, fixed by pre-calculated vaporizing flow in double time intervals. The group II underwent surgical periostal scratching in the medial tibial ssurface at the proximal shaft. Rabbits breathed spontaneously. Hypotension hypercapnia and respiratory acidosis were characteristic of the cardiopulmonary effects of the anesthesia. The corneal reflex and pinch reflex was useful as reliable indicators of anesthetic depth. Manual or mechanical ventilation should be considered as a way of improving alveolar ventilation and normalize blood-gas values. The system developed by Fonseca and Goldenberg was considerede suitable for anesthetic management in rabbits.