ABSTRACT
@#AIM: To investigate the correlation between macular morphology and visual acuity and visual deformation in acute central serous chorioretinopathy(CSC). <p>METHODS: A cross-sectional clinical case-control study was conducted in which 38 patients with acute monocular CSC(CSC group)and 38 normal eyes(control group)were included. The best corrected visual acuity(BCVA), slit lamp microscope, indirect ophthalmoscope, frequency domain optical coherence tomography(OCT), color fundus photography and M-charts were performed in all subjects. The BCVA was converted to the minimum resolution angle LogMAR record when doing statistical. The mean LogMAR, macular retinal thickness(CFT), subretinal fluid thickness(SRF), transverse diameter length of subretinal fluid in macular area and visual deformation(M value)were significantly different between the two groups. The correlation between CFT and SRF, transverse diameter length of subretinal fluid in macular area and M value was analyzed. <p>RESULTS: The mean BCVA in acute CSC group was 0.15±0.15(LogMAR), that in control group was 0.12±0.12(LogMAR); CFT was 418.89 ±134.74μm in CSC group and SRF was 286.95±136.77μm in CSC group. The length of subretinal fluid transverse diameter in macular area was 2926.37±1109.66μm. CFT in control group was 217.58±12.49μm, SRF was 0, and the transverse diameter of subretinal fluid in macular area was 0. The M value of CSC group was 0.86±0.40, MH and MV were 0.99±0.38, 0.73±0.43, respectively. Compared with MV, MH was obviously aggravated, the difference was statistically significant(<i>t</i>=4.564, <i>P</i><0.01). There was no correlation between BCVA and the degree of visual deformation in CSC group(<i>r</i>=-0.124,<i> P</i>>0.05). In CSC group, BCVA had no correlation with SRF or the length of subretinal fluid transverse diameter in macular area(<i>r</i>=-0.059, -0.12; <i>P</i>=0.73, 0.48; respectively.)There was a positive correlation between CFT and M value in CSC group(<i>r</i>=0.91, <i>P</i><0.01). The value of MV was positively correlated with the length of transverse diameter of subretinal fluid in macular area(<i>r</i>=0.934, <i>P</i><0.01), and the value of MH was positively correlated with SRF(<i>r</i>=0.949,<i> P</i><0.01). <p>CONCLUSION: In acute CSC group, BCVA had no correlation with CFT, SRF, macular subretinal fluid transverse length and visual deformability, and visual deformability was positively correlated with CFT, SRF and macular subretinal fluid transverse length; MV was positively correlated with subretinal fluid transverse length, and MH was positively correlated with SRF.
ABSTRACT
Objective To investigate the causes,diagnostic methods,prevention and cure of postmenopausal bleeding(PMB).Methods The clinical and pathological data of 210 PMB patients admitted in this hospital were retrospectively analyzed.Results The causes for PMB were benign diseases(69.5%),the most of which were infec- tious diseases(49.5%),non-organic disease(20.5%)and malignant tumor(10.0%).Compared with benign diseases and non-organic diseases,the attack age of malignant tumor was higher[(67.1?6.9)years old],menopausal dura- tion was longer(11.6?2.9)years,bleeding duration was longer[(157.6?26.4)days],and mucous membrane was obviously thickened[(14.6?3.2)mm](P0.05).Conclusion The main cause for PMB is benign diseases,followed by non-organic diseases.More attentions should be paid to the PMB patients with higher attack age,longer menopausal duration and bleeding dura- tion,and obviously thickened mucous membrane,so as to be precautions to the occurrence of malignant tumor.
ABSTRACT
Objective To detect the concentrations of plasma matrix metalloproteinases-9(MMP-9)and tis- sue inhibitor of matrix metalloproteinase-1(TIMP-1)of patients perioperatively with breast carcinoma,to investigate their relationships with tumor progress,and to could evaluate patients'condition by dynamic detection of plasma MMP-9 and TIMP-1.Methods The perioperative plasma concentrations of MMP-9 and TIMP-1 in patients were detected by ELISA technique in 42 cases breast carcinoma.Results The preoperative concentrations of plasma MMP-9 and TIMP-1 were significantly higher in breast carcinoma than those in normal control(P