Studies on the chemical constituents in herb of Ranunculus japonicus / 中国中药杂志

<p><b>OBJECTIVE</b>To isolate and determine the chemical constituents from Ranunculus japonicus.</p><p><b>METHOD</b>Compounds were isolated by column chromatography, and identified by MS, NMR data.</p><p><b>RESULT</b>Nine compounds were obtained andelucidated as scoparone (1), tricin (2), protocatechuic acid (3), luteolin (4), anemonin (5), scopoletin (6), 5-hydroxy-6, 7-dimethoxyflavone (7), 5-hydroxy-7, 8-dimethoxyflavone (8), ternatolide (9), respectively.</p><p><b>CONCLUSION</b>Compounds 1-9 were isolated from R. japonicus for the first time while compounds 7, 8 were separated from Ranunculus genus first time.</p>