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China Journal of Chinese Materia Medica ; (24): 766-769, 2003.
Article in Chinese | WPRIM | ID: wpr-282244

ABSTRACT

<p><b>OBJECTIVE</b>To study the effects of the extract from bergamot and boxthorn on the skin and the hair growth in mice.</p><p><b>METHOD</b>The skin on the back of mice was shaved topically and smeared with bergamot and boxthorn extract for 42 days. Then the activity of superoxide dismutase (SOD) and the content of malondialdehyde (MDA) and collagen in the mice were measured. The growth of hair was also observed.</p><p><b>RESULT</b>Compared with control group, the extract from bergamot and boxthorn obviously increased the activity of superoxide dismutase (P < 0.05) and the content of collagen (P < 0.001), and decreased the content of malondialdehyde (P < 0.05) in the skin of mice. It also significantly promoted the growth of hair (P < 0.001).</p><p><b>CONCLUSION</b>The extract from bergamot and boxthorn plays an active role in skin and the promotion of hair growth.</p>


Subject(s)
Animals , Female , Male , Mice , Citrus , Chemistry , Collagen , Metabolism , Drugs, Chinese Herbal , Pharmacology , Hair , Lycium , Chemistry , Malondialdehyde , Metabolism , Mice, Inbred ICR , Plants, Medicinal , Chemistry , Random Allocation , Skin , Metabolism , Skin Aging , Superoxide Dismutase , Metabolism
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