Herramienta de alfabetización informacional dirigida a bibliotecarios de ciencias médicas en la provincia de Artemisa, Cuba / Informational alphabetization tool directed to people who work in the medical sciences libraries in Artemisa province, Cuba

Resumen El logro de este proceso informacional en la salud se encuentra centrado en el personal bibliotecario, por lo que resulta necesario fortalecer su desempeño en correspondencia con la identificación de sus necesidades de aprendizaje mediante la aplicación de una herramienta de alfabetización informacional en la provincia de Artemisa, Cuba durante el curso del período 2016-2017. Se realizó una investigación organizada por dos momentos y, con el empleo de métodos empíricos y teóricos, se propuso una herramienta de alfabetización informacional en soporte digital. La metodología utilizada se basó en un medio de enseñanza-aprendizaje de tipo software educativo. La herramienta contribuirá a la calidad en el desempeño del personal que labora en la red de bibliotecas médicas de la provincia de Artemisa.

Abstract The performance of librarians in the medical sciences is enhanced by identifying their training needs through the use of an information literacy tool. We performed this study between 2016 and 2017 with the staff of the medical libraries network at Artemisa province in Cuba. In the first stage of the study we assessed the initial state of the staff's information literacy, and in a second stage, we used empiri-cal and theoretical methods to propose an information literacy tool in digital format. The methodology used was based on educational software. The tool will contribute to enhancing the performance of librarians working in the network of medical libraries in the prov-ince of Artemisa, Cuba.

Possible roles of nitric oxide and peroxynitrite in murine leishmaniasis

Activated macrophages simultaneously synthesize nitric oxide and superoxide anion which can react with each other producing peroxynitrite. Consequently, it has been difficult to assess the precise contribution of each of the formed reactive oxygen- and nitrogenderived species to the microbicidal activities of macrophages, particularly in vivo. To explore this problem, we are examining the formation and potential roles of nitrogen-derived intermediates in Leishmania amazonensis murine infection. Thus far, our results have demonstrated that peroxynitrite is a potent leishmanicidal agent in vitro and that both nitric oxide and peroxynitrite are formed during infection of susceptible BALB/c mouse strain. Nitric oxide was detected as the nitrosyl-hemoglobin complex by electron paramagnetic resonance analysis of blood drawn from mice at different times of infection, and it was shown to increase with the evolution of the disease. These results will be discussed in the context of the dual physiological role of nitric oxide either as a signaling molecule or as a deleterious agent.

Recent advances in vasodilatador therapy Part 1: Physiologic correlations.

La respuesta hemodinamica obtenida de la administracion de agentes vasodilatadores a pacientes con fallo congestivo cardiaco va a depender de su efecto relativo en las arteriolas y venas. Aquellos vasodilatadores que predominantemente causan dilatacion arteriolar, aumentan el debito cardiaco sin cambios significativos en la presion de cuna pulmonar. Aquellos que son vasodilatadores venosos disminuyen la presion de cuna pulmonar sin causar cambios significativos en el debito cardiaco. Los efectos hemodinamicos en pacientes con infarto agudo del miocardio y decompensacion cardiaca van a depender del valor o nivel inicial de la presion telediastolica del ventriculo izquierdo. El rastreo hemodinamico es indispensable en situaciones agudas, para determinar los efectos hemodinamicos de este tipo de terapia