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1.
Rev. med. Rosario ; 84(2): 94-99, mayo-ago. 2018. ilus
Article in Spanish | LILACS | ID: biblio-1050966

ABSTRACT

El autor desarrola los principales hitos en la historia de la angina de pecho o angor pectoris, desde el denominado papiro de Ebers hasta nuestros días


The author develops the main milestones in the history of angina pectoris or angor pectoris, from the so-called Ebers papyrus to the present day


Subject(s)
Humans , History, Ancient , History, 18th Century , History, 19th Century , History, 20th Century , Angina Pectoris/history , Heart Diseases/history , History of Medicine
3.
Rev. med. Rosario ; 81(1): 32-39, ene.-abr. 2015. ilus
Article in Spanish | LILACS | ID: lil-758455

ABSTRACT

Si bien las hojas de digital purpúrea (Digitalis purpurea) se empleaban desde el año 500 D.C., fue el Dr. WilliamWhitering, de Inglaterra, quien investigó sus propiedades y en 1785 escribió un libro que ingresó entre los clásicos de la historia de la medicina: An account of the foxglove and some of its medical uses, with practical remarks on dropsy and other diseases. Esta revisión repasa la historia de la digital, su mecanismo de acción, y los trabajos más recientes que revaloran los efectos de esta medicación, recomendada actualmente a menores dosis de digoxina que las clásicamente aceptadas, capaz de reducir las hospitalizaciones y mejorar la sobrevida, en especial en pacientes con grados avanzados de insuficiencia cardíaca y medicados con inhibidores de la enzima convertidora de angiotensina, beta-bloqueantes, antagonistas de la aldosterona y diuréticos. Quizás aún falta precisar su valor definitivo, pero es indudable que la digital marcó una etapa definitiva en los dominios de la Cardiología y que, junto a la amapola, la quina y la belladona, constituye el grupo de las cuatro principales plantas que han llevado alivio a las enfermedades del hombre


Although the leaves of Digitalis purpurea had been used since 500 D.C., it was the English physician William Withering who studied its properties. In 1785 he wrote the book called “An account of the foxglove and some of its medical uses: with practical remarks on dropsy and other diseases” which became one of the classics in the history of medicine. This article reviews the history of digitalis, its mechanism of action, and recent studies which underline the importance of this medication. Digitalis is presently prescribed at lower doses than tradionally indicated; it is effective in reducing hospital stays, and improving survival, especially in patients with advanced stages of heart failure and receiving inhibitors of the angiotensin converting enzyme, beta-blockers, aldosterone antagonists, and diuretics.Even though its definitive value is yet to be determined, it is certain that digitalis has a role to play in the domains ofCardiology and belongs to the group of the four principal plants that have brought relief to human diseases, along with the poppy, Peruvian bark, and belladona


Subject(s)
Humans , Digitalis/pharmacology , History of Medicine , Heart Failure/prevention & control , Heart Failure/therapy , Cardiology/history , Pharmacology/history , Review Literature as Topic , Plants, Medicinal
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