ABSTRACT
Hospital volunteer service is in line with the needs of modern society members. Further pushing the hospital volunteer service towards institutionalization, standardization and normalization meets the health service needs of different patients to a large extent, which is an indispensable part of the medical and health system reform. This paper analyzes the current hospital volunteer service in our country using SWOT method. It should utilize the external opportunities, give play to the inherent advantages, avoid external threats, and reverse the internal weak-nesses, to achieve long-term development of the hospital volunteer services.
ABSTRACT
Objective:To determine the antioxidization and antiproliferation of extract from leaves of Toona sinensis (LTS).Methods:The total phenolic extract of LTS was obtained by solvent and polyamide resin to determine the content.The antioxidization of the LTS extract was measured by TOSC assay.Antiproliferation was studied in vitro with different human cancer cells.Results:The total phenolic content in the LTS was (427.53±4.31) mg/g and antioxidization was 807.64 μmoL vitamin C equivalents/g in the sample.The extract significantly inhibited the colon cancer cell Caco-2,human liver cancer cell HepG2 and breast cancer cell MCF-7 proliferation with EC50 (4.00±0.39),(153.16±13.49) and (193.46±14.68) μg/mL,respectively.The bioactivity index (BI) of the LTS extract was nearly 283.Caco-2 was more sensitive than MCF-7 and HepG2.Conclusion:Extract from LTS has anticancer properties useful for preventing chronic diseases.
ABSTRACT
BACKGROUND: Polysaccharide sulfate has bean hot focus in recent research.Regarding anticoagulant property of sulfated polysaccharides, recent studies mainly explored degree Of substitution, and there are rare studies concerning relative molecular mass and spatial structure.OBJECTIVE: To study the anticoagulant activity of the sulfated agarose with different relative molecular masses.METHODS: With formamide as dispersing agent,agarose was sulfated with the method of chlor0sulfonic acid-pyridine.The product was graded and purified with dialysis bag.Two kinds of sulfated agarose with different molecular masses were obtained,and their anticoagulant properties were checked by assays of the activated partial thromboplastin time,thrombin time.RESULTS AND CONCLUSION:.Two kinds of sulfated agarose had similar degree of substitution and sulfation position,whereas their molecular weight was different.The bioassay results of coagulation index demonstrated that the anticoagulant activity of agarose improved with the increasing of molecular mass within a certain range.Relative molecular mass had an important effect on the anticoagulant activity of the sulfated agarose.