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The former Ministry of Health launched a project regarding National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases (NCDs) in 2010.This study combined quantitative and qualitative methods,using epidemiological,anthropological and sociological methods to carry out process assessment,effectiveness and case study to evaluate the outcomes of the Demonstration Areas in China.A government leading body,under multi-sectoral cooperation pattern set for prevention and control of NCDs in the Demonstration Areas,was established.All the health related indicators of the residents from the NCDs appeared better than the national average level,showing the fact that the first phase goal on the establishment of Demonstration Areas was materialized.Papers that included in this issue "Evaluation on China National Demonstration Areas for NCDs Prevention and Control" elaborated the implementation status and effectiveness of the Demonstration Areas.It was our hope to provide reference for scaling up the Demonstration Areas and dynamic management in the future.
ABSTRACT
The former Ministry of Health launched a project regarding National Demonstration Areas for Comprehensive Prevention and Control of Non-communicable Diseases (NCDs) in 2010.This study combined quantitative and qualitative methods,using epidemiological,anthropological and sociological methods to carry out process assessment,effectiveness and case study to evaluate the outcomes of the Demonstration Areas in China.A government leading body,under multi-sectoral cooperation pattern set for prevention and control of NCDs in the Demonstration Areas,was established.All the health related indicators of the residents from the NCDs appeared better than the national average level,showing the fact that the first phase goal on the establishment of Demonstration Areas was materialized.Papers that included in this issue "Evaluation on China National Demonstration Areas for NCDs Prevention and Control" elaborated the implementation status and effectiveness of the Demonstration Areas.It was our hope to provide reference for scaling up the Demonstration Areas and dynamic management in the future.
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Objective: To analyze the current status of anticoagulant therapy for in-hospital patients with acute coronary syndromes (ACS) at county hospitals of China and to explore the relationship between anticoagulant therapy and clinical outcomes in real medical environment. Methods: 99 county hospitals from15 provinces of China were selected for this prospective registry study and 12373 eligible ACS patients without interventional therapy admitted from 2011-09 to 2014-06 were enrolled. The basic condition, previous history, initial assessment, anticoagulants (unfractionated heparin/low molecular weight heparin) application, severe bleeding events and in-hospital mortality were collected in all patients. Multiple logistic regression analysis was conducted to explore the relationship between anticoagulant therapy and clinical outcomes including in-hospital mortality, severe bleeding events and combined endpoints; meanwhile, possible confounders were adjusted. Results: A total of 9985/12373 ACS patients received anticoagulant therapy and 2388 did not. Anticoagulant therapy was conducted in 92.7% (4237/4570) patients with ST-segment elevation myocardial infarction (STEMI), 90.8% (1639/1805) with non-ST-segment elevation myocardial infarction (NSTEMI) and 68.5% (4109/5998) with unstable angina (UA); there were differences by regions and genders,P0.05. Meanwhile, it did not increase the risk of severe bleeding events in ACS patients,P>0.05. Conclusion: Anticoagulant therapy has been widely used in STEMI and NSTEMI patients at county hospitals of China and obviously decreased the in-hospital mortality; while the application rate was relatively low in UA patients. The general safety of anticoagulant therapy has been good in ACS patients.
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Objective: To understand the gender disparity and influencing factors for in-hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) at secondary hospitals in China. Methods: A total of 5525 in-hospital STEMI patients from 99 secondary hospitals of 15 provinces or autonomous regions between 2011-09 to 2014-06 were recruited including 1649 female and 3876 male. The in-hospital mortalities were compared between 2 genders and the relevant inlfuencing factors were studied by multiple Logistic regression analysis. Results: There were about 29.8% female and 70.2% male STEMI patients were studied. The in-hospital mortalities in female and male were 13.2% and 5.9%,P<0.01; gender disparity was obviously existing regardless of age, history of MI, hypertension and diabetes mellitus. The mortality in female was higher than male even without diseases history and cardiovascular risk factors. Compared with male gender, female patients were usually having elder age and likely complicated with cardiovascular risk factors; they were with lower incidence to receive ECG, drug therapy and thrombolysis within 10 minutes of admission. With adjusted confounding factors, multiple regression analysis presented that female STEMI patients had the higher mortality than male (OR:1.7, 95% CI:1.4-2.0). Conclusion: The in-hospital mortality for STEMI patients was higher in female than male at secondary hospitals in China. Female patients were usually having elder age, complicated with more cardiovascular risk factors, while with less chances to receive ECG, drug therapy and thrombolysis within 10 minutes of admission.
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Objective To assess effectiveness of implementation of non-pharmaceutical treatment in a standardized community-based hypertension management program in China.MethodsA protocol of standardized community-based hypertension management was developed based on current guidelines for prevention and treatment of hypertension in China.Physicians in community health-care service centers at the grassroots across China were trained in a standardized way using this protocol during 2005 to 2008,and then the trainees were required to manage hypertensive patients according to the protocol.Hypertensive patients eligible for criteria of inclusion and under management for more than one year were analyzed to observe changes in their behavioral risk factors,pharmaceutical and non-pharmaceutical treatment,and effectiveness of blood pressure lowering.ResultsBy the end of 2008,a total of 29 411 hypertensive patients had been managed for one year according to the protocol and 20 077 patients with complete data (47.1％ for male)with mean age of 61±11 years were eligible for analysis.After standardized management of one year,prevalence of smoking,alcohol drinking and proportion of patients who preferred salty diet decreased from 17.7 percent,18.1 percent and 32.8 percent to 8.9 percent,8.7 percent and 15.8 percent,respectively(P＜0.01).Srstolic blood pressure(BP)decreased by 11.6[95％confidence interval(CI)10.8-12.4]mm Hg(1 mm Hg=0.133 kPa),13.7(95％CI 13.3-14.1)mm Hg and 15.2(95％CI14.8-15.6)mmHg in the patients with non-pharmaceutical therapy,pharmaceutical therapy and both,respectively；and diastolic BP decreased by 7.5(95％CI6.9-8.1)mm Hg,8.3(95％CI8.1-8.5)mmHg and 8.0(95％CI7.8-8.2)mm Hg in the three groups,respectively.During the one-year period of management,proportion of the patients with appropriate non-pharmaceutical therapy increased continuously.By the end of one-year management,59.5 percent of smoked patients were required to quit their smoking,55.5 percent of alcohol drinkers were required to limit their drinking,52.3 percent of overweight and obese patients were required to reduce their weight and 47.3 percent of patients with physical exercises less than three times a week were required to increase their regular physical activity.However,certain proportion of the patients with risk factors did not receive appropriate non-pharmaceutical therapy.Conclusion Guideline-oriented hypertension management succeeded in lifestyle changes among the patients,but it is a gradual process to its full implementation.
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Objective To investigate the impact of high plasma LDL-C level with or without metabolic syndrome(MS) on the incidence of stroke in Chinese adults. Methods Totally 42 626 subjects (25 -75 years old) from Chinese National Health and Nutrition Survey in 2002 were stratified four groups based on plasma LDL-C level: < 2. 00 mmol/L group, 2. 00 -2. 50 mmol/L group, 2. 51 -3.31 mmol/L group, and ≥ 3.32 mmol/L group. The prevalence of MS (with 2005 International Diabetes Federation criteria) and stroke and the risk factors of stroke were compared among the four groups. Results ( 1 ) The prevalence of MS and stroke increased with rising of LDL-C level. The prevalence of MS in LDL-C≥3. 32 mmol/L group increased 2. 5 times (7, 9% vs 20. 1% ) as compared with that in LDL-C < 2. 00 mmol/L group and the prevalence of stroke increased 4. 2 times(0. 5% vs 2. 1% ), all P <0. 01. (2) In subjects with similar LDL-C level, the prevalence of stroke was significantly higher in a subgroup with MS than that without (P <0. 01 ). (3) After adjustment for age, sex and smoking, logistic regression analysis showed that both LDL-C level and MS were positively associated with the development of stroke; the odds ratio (OR) was 2. 35 and 3. 15 ( P < 0. 0001 ), respectively. (4) Compared with the subgroup of LDL-C < 2. 00 mmol/L without MS, OR for stroke in the subgroups of LDL-C 2. 00 -2. 50 mmol/L, 2. 51 -3. 31 mmol/L, and ≥ 3. 32 mmol / L without MS was 1.03, 1. 89, and 2.08, whereas the OR for stroke in the subgroups with MS and similar level of LDL-C was 4. 38, 5.23 and 6. 15 ; this indicated that the risk of stroke in subjects with MS increased by 3 - 4 times compared with subjects without ( P < 0. 0001 ). Conclusion Both high LDL-C level and MS are independent risk factors of stroke, but the risk of stroke will be further increased in the presence of high LDL-C level plus MS. It is suggested that combined intervention therapy of LDL-C and MS will play an important role in the prevention of stroke.
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Objective: To analyze the drinking practice of people in China. Method: The data of 2002 China National Nutrition and Health Survey was used for this study. 159 117 subjects aged 15 years and over were involved. The information on drinking practice was collected using interview-administrated questionnaire. Results: The overall current drinking rate of people in China was 21.0%, 39.6% for male and 4.5% for female, respectively. The current drinking rates in urban and rural areas were 20.9% and 21.0%, respectively. The 45 to 59 years age group reached the highest. The rate of onset age of drinking younger than 18 years old was 8.8% in current drinkers. 39.9% male and 29.5% female current drinkers drank at least once a day. Distilled spirits was the first choice for 50.3% current drinkers. 58.2% male drinkers and 77.3% female drinkers consumed 100-150g and 50-100g distilled spirits, respectively. Conclusion: Alcohol drinking has become a public health problem in China, it is necessary to carry out further surveys to reveal the influencing factors.
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<p><b>OBJECTIVE</b>To estimate the current knowledge on hypertension and the effect of management on hypertension in patients attending hospital clinics.</p><p><b>METHODS</b>A cross-sectional survey was used in the outpatients over the age of 35 years in 18 general hospitals (provincial, district and community) which represented the different levels of medical care in 8 major cities covering Northern and Southern China including an interview with two blood pressure measurements and one questionnaire in one clinical visit.</p><p><b>RESULTS</b>A total of 9 703 subjects participated in this project, who were similarly distributed by gender and age in the hospitals at different levels. Of all the 9 703 subjects, 4 510 (46.5%) were found to be hypertensive. 6.4%, 12.1%, 25.5%, 41.1% and 14.6% of all the participants were categorized into knowledge on hypertension grade 0, 1, 2, 3, 4 respectively. The classification was based on the number of correct answers to four questions about knowledge of hypertension. The higher the grade of hypertension knowledge the more response to higher rate of awareness, treatment, and control in this hypertensive population was noticed. There was significantly positive correlation between the grade of hypertension knowledge and treatment compliance. The major cause of poor treatment compliance was due to lack of hypertension knowledge.</p><p><b>CONCLUSION</b>There was poor knowledge on hypertension in the investigated participants, which would influence on the management of hypertension. Data suggested that health education on the knowledge of hypertension in the population needs to be improved.</p>