ABSTRACT
Objective To evaluate MRI findings and X ray appearance in primary myelofibrosis (PMF) in marrow of lumber vertebra and pelvis. Methods Eleven cases of PMF with integrated clinical and pathology data were collected. All cases were examined with X ray and MRI simultaneously. The imaging findings of PMF were studied and compared with that of normal group. The MRI findings and X ray appearance of cases with PMF were evaluated and compared with each other to find their good quality, the shortcoming, and the relationships. Results X ray appearance in the plain film in cases with PMF: There were no abnormal findings in lumbar vertebra, iliac bone, and superior segment of femur in 5 of 11 cases. Blurred bone trabecula and ground glass changes in bone marrow were found in 3 of 11 cases. In another 3 cases, the bone trabeculas were obscured, tightly closed or mixed together, and the density of bone marrow were widespreadly high, and the difference in it couldn′t be distinguished. MRI findings in cases with PMF: MRI findings in different parts of lumbar vertebrae, iliac bone, and femur superior segments in all 11 cases were consistent. Compared with the control group, both images on T 1 and T 2 weighted spin echo displayed diffusely and well distributed lower signal intensity in 6 of 11 cases, but displayed scattered spot and patchy lowersignals in 5 of 11 cases in all parts of bone marrow including lumbar vertebra, iliac bone, and superior segment of femur. The extents of lower marrow signal intensity varied in different cases. The high signal in femoral head and greater trochanters remained unchanged as that of subcutaneous fat in 4 of 11 cases. The positive rate was 54.6%(6/11)in X ray findings, but 100%(11/11)in MRI appearances. Conclusion MRI has greater value than X ray in the early diagnosis of PMF. The early diagnostic value of X ray plain film for PMF is limited.
ABSTRACT
Objective To improve the understanding of the radioactive charcteristics of vertebral eosinophilic granuloma.Methods The imaging features (X-ray?CT and MRI) of 10 cases with vertebral eosinophilic granuloma were retrospectively analyzed.Diagnoses of all the patients had been confirmed with pathlolgical examination after operation.Results All the patients had vertebral body damages,7 with osteolytic damages and 3 with cystic damages.Intervertebral crevice became narrowing or disappearing .Some vertebral appendix and paravertebral soft tissue were involved.Conclusion It is out of proportion among the vertebral body damages,the involved vertedral arch,the changes of intervertebral crevice and the mass of paravertebral soft tissue.The remaining bone fragment without sequestrum in the damage ares is considered as the main characteristic expression of vertebral eosinophilic granuloma.