ABSTRACT
Objective To analyse the clinical efficacy of combined intra-arterial and intravenous(IA/IV) versus single intravenous(IV) thrombolysis using recombinated tissue plasminogen activator( rt-PA ) for acute cerebral infarction.Methods 20 patients with acute cerebral infarction were treated with IA/IV (10 patients) versus IV (10 patients) thrombolysis using rt-PA. Europe stroke scales (ESS) and Barthel Index (BI) scores were analyzed respectively both before and after the thrombolysis for the 20 patients. Therapeutic effects and adverse effects were observed.Results Total and partial recanalization of the occlusion arteries were showed in 8 and 2 IA/IV patients respectively, and the ESS and BI scores of IA/IV patients were significantly higher than those of IV patients(all P