ABSTRACT
BACKGROUND: MRI is a gold standard for imaging diagnosis of knee joint disease, but it cannot accurately quantitate effusion of knee.OBJECTIVE: To investigate different volume of contrast-medium in the cavity of knee with MRI scanning to provide objective evidence and quantitaive standard for clinical diagnosis of effusion in the cavity of knee.DESIGN, TIME AND SETTING: Quantitative observation was performed in the MRI Room, the First Affiliated Hospital of Chengdu Medical College from October to December 2008.MATERIALS: Ten samples of fresh normal adult knee joint.METHODS: Puncture with the needle retaining in the cavity of knee of normal adult corpse without effusion or pneumatosis was performed, and 1, 5, 10, 15, 20, 30, 40 mL contrast-medium was injected into the cavity. Coronal section, vertical plane and transect were scanned with T2WI, 4 mm thickness and 1 mm interval by MRI.MAIN OUTCOME MEASURES: The distribution of different amounts of contrast agent in the knee cavity and peripheral synovial bursa in knee coronal plane and sagittal cross-sections.RESULTS:?MRI scanning from coronal section: after 10 mL contrast-medium injection, in the center of medial knee joint, high visual signal was seen in the cavity of joint; after 15 mL contrast-medium injection, scanning between femora and patella, high visual signals were observed; after 20 mL contrast-medium injection, scanning by posterior internal and external condyle of knee, high visual signals were found in 80% of internal and external recess of posterosuperior of thighbone.?MRI scaning at 1.5 cm from internal vertical plane of middle knee: after 5 mL contrast-medium injection, high visual signal area appeared in intercondylar eminence, narrowing gradually, and 70% of posterosuperior internal condyle of tibia; after 10 mL contrast-medium injection, high visual signals appeared at the 1/3 point under suprapatellar bursa; after 15 and 20 mL contrast-medium injection, high visual signal appeared in 80% of 1/3 point of suprapatellar bursa; after 30 and 40 mL contrast-medium injection, high visual signal was seen both internal and external recess of posterosuperior knee.?MRI scanning from inframarginal Apex of patella of knee transect: after 5 mL contrast-medium injection, high visual signal appeared in 90% area at 1/3 point posterior articular cavity; after more than 10 mL contrast-medium injection, high visual signal was seen in 70% area of anterior thighbone facet. CONCLUSION: By injecting different volumes of contrast-medium into the knee cavity and peripheral synovial bursa, reference standard can be constructed according to different volumes of effusion, which is significant for diagnosis of effusion of knee cavity and peripheral synovial bursa with MRI.
ABSTRACT
The article discusses the integration of the contents on the human anatomy and medical imaging.Through construction of the human anatomy and medical imaging course system and the implementation of teaching,we have overcome the defects of separation of anatomy and medical imaging knowledge and received better teaching results.