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Objective To investigate the acceptance status of intemet + health management among hypertensive patients in Xuzhou city and the related influencing factors.Methods An interviewing questionnaire survey on the acceptance of internet + health management was conducted among 1,200 hypertensive patients from Xuzhou community health service centers selected by randomized cluster sampling and stratified sampling methods from February tp August 2018,1 116 valid questionnaires were finally obtained with a response rate of 93.0％.The respondents were divided into two groups according to whether they would accept the internet + health management,and the general conditions and health management status of the two groups were compared.Results The acceptance rate of internet + health management was 71.9％ (802/1 116).The univariate analysis showed that age,education level,occupation,and monthly income of hypertensive patients were associated with the acceptance of internet + health management (P＜0.05);patients with family history of hypertension,cardiovascular and cerebrovascular complications and high health literacy had higher acceptance rate of internet+health management (P＜0.05).Multivariate analysis showed that educational levels of junior high school and above (OR=0.426,0.318,0.089),good sleep (OR=0.453) were protective factors for acceptance of internet+health management;while not knowing the diagnostic criteria for hypertension (OR=1.494),not knowing the blood pressure monitoring (OR=2.668),not knowing ECG monitoring (OR=2.247),quitting smoking (OR=2.444),no complications (OR=2.247),and not participating in community health management (OR=1.758) were the risk factors of acceptance of internet + health management for patients with hypertension.Conclusion The acceptance rate of internet+health management among hypertensive patients in Xuzhou city is relatively high.A variety of factors have impact on the acceptance of internet + health management.
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Objective@#To investigate the acceptance status of internet+health management among hypertensive patients in Xuzhou city and the related influencing factors.@*Methods@#An interviewing questionnaire survey on the acceptance of internet+health management was conducted among 1,200 hypertensive patients from Xuzhou community health service centers selected by randomized cluster sampling and stratified sampling methods from February tp August 2018, 1 116 valid questionnaires were finally obtained with a response rate of 93.0%. The respondents were divided into two groups according to whether they would accept the internet+health management, and the general conditions and health management status of the two groups were compared.@*Results@#The acceptance rate of internet+health management was 71.9% (802/1 116). The univariate analysis showed that age, education level, occupation, and monthly income of hypertensive patients were associated with the acceptance of internet+health management (P<0.05); patients with family history of hypertension, cardiovascular and cerebrovascular complications and high health literacy had higher acceptance rate of internet+health management (P<0.05). Multivariate analysis showed that educational levels of junior high school and above (OR=0.426, 0.318, 0.089), good sleep (OR=0.453) were protective factors for acceptance of internet+health management; while not knowing the diagnostic criteria for hypertension (OR=1.494), not knowing the blood pressure monitoring (OR=2.668), not knowing ECG monitoring (OR=2.247), quitting smoking (OR=2.444), no complications (OR=2.247), and not participating in community health management (OR=1.758) were the risk factors of acceptance of internet+health management for patients with hypertension.@*Conclusion@#The acceptance rate of internet+health management among hypertensive patients in Xuzhou city is relatively high. A variety of factors have impact on the acceptance of internet + health management.
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Objective@#To explore the characteristics of ultrasonography of thyroid papillary carcinoma and normal ultrasound and its significance to determine whether there is a cervical lymph node metastasis.@*Methods@#A total of 80 cases with thyroid papillary carcinoma in our hospital from September 2014 to September 2017 were selected as the research object.According to the results of postoperative pathology, the patients were divided into the neck lymph node metastasis (LNM) and without LNM group.All patients received preoperative normal ultrasound and contrast-enhanced ultrasound examination, the characteristics were summarizd and compared.@*Results@#Histopathology results showed that 45 cases of 80 patients had cervical LNM and 35 cases were not associated with cervical LNM.In LNM group, the contrast agent in cancer nodules was one case, which in the non-LNM group was 4 cases, the difference between the two groups was significant(Z=2.991, P<0.05). As to the blood flow parameters of color doppler ultrasound, the differences in PSV, PI, RI, PSV and PI were not obvious between the two groups(all P>0.05). The RI difference of the LNM group was (0.12±0.04), which was significantly higher than (0.05±0.02) of the non-LNM group, the difference was statistically significant (t=2.271, P=0.021).@*Conclusion@#Conventional ultrasound and contrast-enhanced ultrasound have important value in predicting cervical lymph node metastasis of thyroid papillary carcinoma.
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Objective To investigate the risk factors for postoperative cognitive dysfunction (POCD) and nursing intervention in patients undergoing laparoscopic radical hysterectomy. Methods One hundred patients undergoing laparoscopic radical hysterectomy were included, surgical history, general anesthetics way, education, family factors(alone), body mass index, age, duration of anesthesia, dose of sufentanyl, hematocrit, the time for regaining orientation, dysphoria, postoperative pain degree were recorded. The occurrence of POCD was observed at 7 days (early period) and 3 months (later period) after surgery. Logistic regression analysis was used to examine the risk factors for POCD at early period and later period. Results The incidence of POCD at early period was 29.0%(29/100). Logistic regression analysis of surgical history, general anesthetics way, body mass index, age, hematocrit, the time for regaining orientation, postoperative pain degree in patients, general anesthetics way (OR=2.821, 95%CI 1.099-7.240) and postoperative pain degree(OR=2.292, 95%CI 1.129-4.654) were the significant risk factors for POCD at early period. The incidence of POCD at later period was 7.0%(7/100). Logistic regression analysis of education and family factors(alone) in patients, family factors(alone) was the significant risk factor for POCD at later period (OR=5.517, 95%CI 1.010-30.126). Conclusions General anesthetics way and postoperative pain degree are the significant predictors for POCD in patients undergoing laparoscopic radical hysterectomy during hospitalization, and family factors(alone) is the risk factor for POCD at 3 months after surgery, and active nursing intervention could reduce the occurrence of POCD.
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Objective To investigate the prevalence of obesity and metabolic syndrome(MS)of children and adolescents in Longquan mountainous area in Zhejiang province.Methods A representative sample involving 2 135 children and adolescence aged 10 to 15 years were randomly surveyed and a total of 2 125 had available data(male/female ratios as:1 109/1 016).Using the standard methods,we measured the weight,height,waist circumference,hip circumference,blood pressure,detected fasting plasma glucose (FPG),high density lipoprotein cholesterol (HDL -C),triglyceride(TG),total cholesterol(TC),and calculated non-high density lipoprotein cholesterol(non-HDL). The prevalence of obesity and MS among the 10 to 15 years old children and adolescence in Longquan was compared with that in six cities in China(Beijing,Tianjin,Shanghai,Zhejiang,Chongqing and Guangxi).Results The preva-lence of obesity was 4.7% in 10 -15 -year -old teenage,in which the male obesity prevalence was 6.3%(70/1 109),female obesity prevalence was 3.0%(30 /1 016).The prevalence of overweight was 9.4% and the prevalence of boys was 11.0%,while the girl was 7.6%.The prevalence of obesity and overweight was 16.4%(299/2 125).The prevalence of MS was 2%(42/2 125)in the survey,but 42.0%in the obesity.The prevalence of obesity in Longquan(4.7%)was lower than that in the national six cities(8.1%)among the children and adoles-cents from 10 to 15 years old(χ2 =31.09,P=0.000).But in the obesity students,the prevalence of MS(42.0%)in Longquan was higher than that in six cities(28.8%)(χ2 =5.43,P=0.02).Conclusion The prevalence of obesity in Longquan mountainous area was lower than that in the national six cities among the children and adolescents from 10 to 15 years old.However,the prevalence of MS among the obesity in Longquan was higher than that in six cities.
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Objective This study was designed to determine the expression ofgeneproducts of phosphatase and tensin homoligy deleted onehromoseten(PTEN)and DNA content in non small cell lung cancer(NSCLC)tissue and investigate their association with the invasion and metastasis of NSCLC.Methods The expression of PTEN were detected in 78 cases of lung cancer tissues by immunohistochemistry SP methods,DNA content in 30 cases of lung cancer tissues was examined by flow cytometry.Results The rate of total expression depletion of PTEN was 42.3%.The rates of PTEN expression depletion in lymph node metastasis group and no lymph node metastasis group were 52.1%and 26.7%respectively,with significantant difference(P＜0.05).The patients who had high expression of PTEN had a longer survival time.The range of the DNA index(DI)distribution ranged from 1.04 to 1.93,the DNA index and aneuploid tumor had a positive correlation with the lymph node metastasis,with the increased of TNM stage,the DI and the rate of DNA aneuploid increased(P＜0.05).Conclusions Expression of PTEN is associated strongly with lymph node metastasis of lung cancer,correlations exist between DNA content and TNM stage,lymph node metastasis.They are indications of metastasis potential and prognosis of lung cancer.
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Objective To study the expression of both nuclear factor-κB(NF-κB)and tumor necrosis fac-tor-α(TNF-α)in pulmonary intravascular macrophages(PIM)of rats with hepatopulmonary syndrome (HPS)and the effect of pyrrolidine dithiocarbamate(PDTC)on their expression.Methods The Sprague-Dawley(SD)rats were randomly divided into four groups:control,control+PDTC1CCl4,CCl4+PDTC groups.Arterial blood was collected for measurement of blood gas.Venous blood was sampled for hepatic function and endotoxin level.The mesenteric lymph nodes were dissected for bacteriology studies.Proteins of NF-κB and TNF-a of lung tissue were examined by immunohistochemistry.The activity of NF-κB in lung tissues was measured using electrophoretic mobility shift assay (EMSA).By real-time polymerase chain reaction (PCB)using SYBR Green I,the mRNA expression of TNF-α in lung tissues were detected.Results CCl4 group developed HPS with decreased PaO2 and PaCO2,increased alveolar-arterial oxygen difference(A-aDO2),abnormal hepatic function and increased endotoxin level.Culture-positive mes-enteric lymph nodes were found in 62.5%(5/8)of CCl4,group and 66.7%(6/9)of CCl4+PDTC group(P>0.05 J.All lungs from CCl4 and CCl4+PDTC group showed no accumulation of larse mononuclear macrophagelike cells within the lumen of numerous small muscular and nonnulscular pulmonary vessels.The percentages of vessels with more than 1O adherent macrophages was 60.8%(292/480)in CCl4 group but only 19.6%(106/540)in CCl4+PDTC group(P<0.01).The protein expression of NF-κB and TNF-α Was localized to PIM in CCl4 group.The NF-κB activity and mRNA expression of TNF-α in CCl4 group was significantly higher than that in control,con-trol+PDTC group and CCl4+PDTC group(P<0.05).Conclusion The TNF-α expression in PIM induced by NF-κB play an important role in HPS.The inhibitor of NF-κB PDTC can repress PIM activation and decrease the ex-pression of TNF-α.As result.HPS severity is reduced.
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Objective To investigate the clinical epidemiological characteristic of the cancer in upper digestive tract detected by endoscopy and pathologically diagnosed in Xi'an.Methods Patients with cancer of upper digestive tract,detected by endoscopy and pathologically diagnosed from 1991.1 to 2002.12 were selected.The main clinical data,epidemiologyical,endoscopic manifestation and the pathological characteristics were studied.Results The overall diagnosis rate of upper digestive tract cancer was 8.13% in 12 years.Of all the patients who underwent endoscopy,cancer of esophagus,cardia,stomach and duodenum was 3.42%,1.44%,3.26% and(0.01%),respectively.Although the incidences of esophageal cancer and gastric cancer fluctuated,they showed remarkable decreasing tendency(P=0.000).Meanwhile,the incidence of cardiac adenocarcinoma increased slightly(P=0.000).The male/female ratio of cardiac cancer is 6.29∶1,which is much higher than that of esophageal cancer and gastric cancer(P=0.000).The ratio of squamous cell cancer and adenocarcinoma in esophagus didn't chang in 12 years((P=0.562)),and the adenocarcinoma of esophagus did not show any remarkable tendency (P=0.557).Conclusion Esophageal cancer is the most frequent cancer of upper digestive tract in Xi'an.The detection rate of esophageal cancer and gastric cancer has decreased respectively,and cardiac cancer has increased.Cardiac cancer is different from either esophageal or gastric cancer.