Chemical constituents of a new species of Spongia sponge / 中国中药杂志

Chemical constituents of a new species of Spongia sponge collected from Sanya bay in Hainan province, were analyzed. Nine secondary metabolites 1-9 were isolated. On the basis of their spectroscopic data and chemical degradation, their chemical structures were determined as palmitoyl-heptacosane-1, 3, 5-triol (1), stigmast-4-en-3beta, 6beta-diol (2),2,3-dihydroxypropanyl hentetracosanate (3), sitosterol (4), thymine (5), gorgosterol (6), batyl alcohol (7), uracil (8) and thymidine (9). Palmitoyl-heptacosane-1, 3, 5-triol (1) is a new compound.

Chemical Constituents of the Tunicate Syela canopus from the Dayawan Bay / 分析化学

Two compositions, a sterol mixture and a pure ceramide, were isolated from the extract of a tunicate,Styela.canopus, collected from the Dayawan Bay, Guangdong. The sterols were detected by gas chromatography/mass spectrometry, and their structure was confimed by spectroscopic analysis. The ceramide was identified by spectroscopic analysis. The contents of sterols and the ceramide in the extract were 12% and 0.3% respectively.This was also the first report about the chemical constituents of Sytela. canopus.

Studies on chemical constituents of the marine sponge Clathria fasciculate from the South China Sea(Ⅱ) / 中国海洋药物

Four organic compounds were isolated from the ethyl acetate soluble fraction of the marine sponge Clathria fasciculate which collected from the South China Sea. Their structures were determined by GC-MS, FAB, IR, 1HNMR, 13CNMR and COSY spectra as: clolest-4-en-3-one(Ⅰ). stigmast-4-en-3-one(Ⅱ). (Z)-17-tetracosene-l-ol(Ⅲ) and3-(17Z-tetracosenyloxy)-1 , 2-propanediol(Ⅳ). It's the second report of the first serial studies of the chemical constituents of the marine sponge Clathria fasciculate.

STUDIES ON THE SPONGE SPONGIA OFFICINALIS ( I ) / 中国海洋药物

The chemical constituents of the soponge Spongia officinalis collected from the South China Sea have been studied. This paper reports the isolation and identification of the eight sterols, i.e. , 1 22, 23-methylenecholesta-5, 7-dien-3B-ol, 2 cholesta-5, 7-dien-3B-ol, 3 cholesta-5,7,25-trien-3B-ol, 4 stigmasta-5-en-3B-ol, 5 stigmasta-7,16,25-trien-3p-ol, 6 stigmasta-5,7,22-trien-3B-ol, 7 ergosta-5,7-dien-3B-ol, 8(22-E)-ergosta-7,22-dien-3B-ol, by means of spectroscope and GC-MS methods.

STUDIES ON THE CHEMICAL CONSTITUENTS OF THE MARINE SPONGE HALICLONA SP / 中国海洋药物

The chemical constituents of the marine sponge Haliclona sp. collected from the South China Sea have been studied. An alkanoid 1 and an aryl acid 2 were isolated from the marine sponge and the structure of 1 and 2 were respectively elucidated as 1,3 -dimethylxanthine and p - hydroxybenzoic acid by spectroscopic analysis and elemental analysis.

Studies on the Secondary Metabolites of the Soft Coral Sinularia papillosa / 中药新药与临床药理

Objective Secondary metabolites of the soft coral were studied to find out the lead compound of the drugs. Methods Compounds from the soft coral Sinularia papillosa were obtained by column chromatography and modern isolation methods and their structures were identified by spectrum of UV,IR,NMR,MS,et al. Results Two white amorphous compounds were obtained from the EtOAc (ethyl acetate) fraction,and their structures were identified as pregn-5,20 -dien-3?-ol-3-O-?-L-fucopyranoside (1) and 1-(17Z-tetracose-nyloxy)-1,2 -propanediol (2) by spectral analysis. Conclusion Two compounds are first isolated from the soft coral genus Sinularia,which will be beneficial for the taxonomy of the soft coral and for biogenesis of steroids.