ABSTRACT
Objective To investigate the correlation of left ventricular ejection fraction (LVEF) as well as serum levels of NT-proBNP, Hcy and D-Dimer (D-D) with different traditional Chinese medicine (TCM) syndrome types of chronic heart failure (CHF). Methods A total of 178 CHF patients were divided into heart function normal ejection fracture group (HF?NEF, n=86) and heart function reduction (HFREF, n=92) according to their LVEF performance. Another 35 cases with nor?mal cardiac function were included in control group. All CHF patients was also divided into 3 TCM syndrome types:both de?ficiency of Qi and Yin syndrome group(n=64),Qi asthenia causing blood stasis syndrome group(n=59) andYang defi?ciency water stop group (n=55). All patients were examined with cardiac color doppler and LVEF values were recorded. And serum NT-proBNP、Hcyand D-D levels were all quantified. Results As to serum levels of NT-proBNP, Hcy and D-D, they were higher in HFREF group than those in HFNEF group than those in control group. On the other hand, LVEF was lowest in HFREF group but highest in control group. All differences were statistically significant (P<0.05). Among patient in HFNEF group, LVEF in theYang deficiency water stop groupwas lower than that inboth deficiency of Qi and Yin syn?drome group(P<0.05). Serum levels of NT-proBNP, Hcy, and D-D were not significantly different between different TCM syndrome groups. By contrast, among patients in HFREF group, LVEF values did not differ significantly between different TCM syndrome groups. Serum level of NT-proBNP was lower inboth deficiency of Qi and Yin syndrome groupthan that inQi asthenia causing blood stasis syndrome group than that in Yang deficiency water stop group. As to serum levels of Hcy and D-D, they are higher inYang deficiency water stop groupthat those inboth deficiency of Qi and Yin syndrome group and Qi asthenia causing blood stasis syndrome group(P<0.05). Conclusion Patients with different TCM syn?drome types of CHF present different levels of serum NT-proBNP, Hcy, D-D level and LVEF. Changes of indicators in HFREF groups are more obvious than they did in HFNEF group.
ABSTRACT
ObjectiveTo predict the fluctuating intervals of intraocular pressure readings in mild and medium myopia after photorefractive keratectomy（PRK）．MethodsThe intraocular pressure（IOP）readings of 383 eyes，of which spherical equivalent were less than-6.0 diopters（D）before and over 1 a after PRK，were measured with noncontact tonometer（NCT）．The IOP data were analyzed with paired-sample t test，linear correlation and regression．Regression equation was used to predict the fluctuating intervals of IOP readings after PRK．ResultsThe IOP readings after PRK（10.38±2.08）mmHg were lower than those before PRK（15.43±2.74）mmHg．The difference of IOP readings between before and 1 a after PRK was significant （P＜0.001）．The postoperative IOP readings were related to those of preoperation （r＝0.625，P＜0.001）and the regression equation was Y＝0.474X＋3.064［X＝IOP reading before PRK（mmHg），Y＝IOP reading followed over 1 a after PRK（mmHg）］．If IOP reading before PRK was X0，the 95％ tolerant interval of IOP readings followed over 1 a after PRK was 0.5X0-0.1，0.5X0＋6.3（mmHg）．ConclusionIOP readings before PRK can be used to predict the fluctuating intervals of IOP readings in mild and medium myopia after PRK．