ABSTRACT
ABSTRACT Introduction: Hemophilia is a coagulopathy caused by a deficiency in coagulation factors VIII (hemophilia A) or IX (hemophilia B). It is a chronic disease and, hence, impairs the quality of life (Qol) of the patients. This study aimed to evaluate the Qol of patients with hemophilia using the WHOQOL-bref and the Haemo-A-Qol instruments, its relation to the clinical condition and its sociodemographic variables. Methods: This is a cross-sectional, epidemiological study, comprising 17 patients with hemophilia, registered at the hemocenter, who met the eligibility criteria. Data were collected using three questionnaires: a semi-structured clinical evaluation form, the WHOQOL-bref and the Haem-A-Qol. Results: The average age was 30 years old, and most participants declared themselves to be single (58.82%), without children (64.70%) and employed (58.82%). Hemophilia A was observed in 14 patients and the most severe form of the disease was more prevalent (64.70%). The average score of Qol, estimated by the WHOQOL-bref questionnaire was 74.3; being "social relations" the domain with the highest average. The Haem-A-Qol measured an average of 36.2 and the domain with the highest result was "Family Planning". Conclusion: Hemophilia had a higher negative impact upon the physical, sports and leisure features in the sample subjects. The analysis of the questionnaires did not reveal statistical agreement between them. Based on this, the Haem-A-Qol is considered the most recommended to evaluate the Qol, as it addresses factors more specifically related to the disease. No statistical significance was observed between the scores of Qol, as for the presence of comorbidities, gravity of the hemophilia and positive serology for infections.
Subject(s)
Humans , Adult , Middle Aged , Quality of Life , Surveys and Questionnaires , Hemophilia AABSTRACT
RESUMO Objetivo: Sistematizar as referências da literatura relacionadas à associação entre consumo de bebidas açucaradas não alcoólicas, leite e índice de massa corporal (IMC) em adolescentes. Fontes de dados: Realizou-se a pesquisa dos artigos nos portais PubMed (US National Library of Medicine National Institutes of Health) e BVS (Biblioteca Virtual em Saúde). Os descritores foram: adolescente, adulto jovem, bebidas, ingestão de líquidos, obesidade, sobrepeso, IMC e estado nutricional. Utilizaram-se os filtros: idade entre 10 e 19 anos e artigos em português e inglês, publicados entre 2011 e 2015. Síntese dos dados: Trinta estudos foram selecionados (22 transversais, 4 coortes, 1 ensaio clínico aleatório, 1 caso-controle e 1 quase experimental). Dos 20 estudos que abordaram bebidas açucaradas em geral, 55% encontraram associação entre consumo e aumento do IMC. Em relação aos estudos sobre a ingestão de refrigerantes, todos apresentaram associação entre consumo e aumento do IMC. Dos estudos sobre leite, somente um demonstrou associação entre consumo e aumento do IMC. Três artigos mostraram proteção entre consumo de leite e aumento do IMC, e três trabalhos não encontraram associação de seu consumo com aumento do IMC. Dezenove estudos possuíam amostras representativas e outros 20 declararam ter amostras aleatórias. Dos artigos com questionários, 84% eram validados. Conclusões: Verifica-se que não há consenso na literatura pesquisada sobre a associação entre consumo de bebidas açucaradas não alcoólicas, leite e IMC de adolescentes.
ABSTRACT Objective: To systematize literature references addressing the association of sugar-sweetened beverage (SSB) and milk intake with body mass index (BMI) in adolescents. Data source: A search was carried out in PubMed (US National Library of Medicine National Institutes of Health) and BVS (Virtual Library in Health). The descriptors used were: adolescents, young adult, beverages, drinking, obesity, overweight, BMI, and nutritional status. The following filters were applied: age ranging from 10 to 19 years, studies published in Portuguese or English language between 2011-2015. Data synthesis: Thirty studies were selected (22 cross-sectional studies, 4 cohort studies, 1 randomized clinical trial, 1 case-control study, and 1 quasi-experimental study). There was association between the intake of these beverages and increase in BMI in 55% of all 20 studies that dealt with sugary drinks. When it came to soft drinks, 100% of studies reported association with increase in BMI. As to milk intake, only one article showed association with increased BMI. Three articles reported milk as a protection factor against increase in BMI; three studies found no association between this intake and BMI. Nineteen studies had representative samples and 20 surveys reported random samples. Among papers using questionnaires, 84% had been validated. Conclusions: There is no consensus in the literature about the association between SSB or milk intake and BMI in adolescents.