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Rev. bras. reumatol ; 48(5): 313-316, set.-out. 2008. ilus
Article in Portuguese | LILACS | ID: lil-500208

ABSTRACT

Entre os vários tipos de inflamação ocular associados às doenças reumatológicas, a uveíte anterior é particularmente comum nas espondiloartropatias, em especial quando associada à presença do genótipo HLA-B27. Relatou-se o caso de um paciente com artrite indiferenciada HLA-B27 positivo, complicado com panuveíte e vasculite da retina, refratária ao tratamento imunossupressor tradicional, que obteve boa resposta clínica ao uso de anti-TNF-alfa.


Among the several types of ocular inflammation associated to the rheumatic diseases, anterior uveitis is particularly common in the spondyloarthropathies, especially when associated to the presence of the HLA-B27 genotype. We report the case of HLA-B27 positive patient with undifferentiated arthritis, complicated with panuveitis and retinal vasculitis, that was refractory to the traditional imunossupressive treatment, and had a good clinical response with anti-TNF-alpha therapy.


Subject(s)
Humans , Male , Adult , Arthritis , Panuveitis , Retinal Vasculitis , Rheumatic Diseases , Tumor Necrosis Factor-alpha , Uveitis , Uveitis, Anterior
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