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West Indian med. j ; 61(1): 106-108, Jan. 2012. ilus, tab
Article in English | LILACS | ID: lil-672860

ABSTRACT

We report a case of successful treatment with erlotinib of a patient with non-small cell lung cancer (stage IV) and meningeal metastasis. Combined treatment with whole brain radiotherapy (WBRT) and erlotinib mitigated neurologic symptoms of the patient. Magnetic resonance imaging showed reduction of the brain metastasis. Partial remission was observed by chest computed tomography (CT) scan after six months of erlotinib therapy.


Reportamos un caso de tratamiento exitoso con el erlotinib de un paciente con cáncer pulmonar de células no pequeñas (fase IV) y metástasis meníngea. El tratamiento combinado con la radioterapia total del cerebro (WBRT) y erlotinib mitigaron los síntomas neurológicos del paciente. Las imágenes de resonancia magnética mostraron una reducción de la metástasis del cerebro. La remisión parcial fue observada mediante CT scan de tórax tras seis meses de terapia con erlotinib.


Subject(s)
Aged , Humans , Male , Carcinoma, Non-Small-Cell Lung/drug therapy , Carcinoma, Non-Small-Cell Lung/radiotherapy , Lung Neoplasms/pathology , Meningeal Neoplasms/drug therapy , Meningeal Neoplasms/radiotherapy , Carcinoma, Non-Small-Cell Lung/secondary , Meningeal Neoplasms/secondary , Protein Kinase Inhibitors/therapeutic use , Quinazolines/therapeutic use
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