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National Journal of Andrology ; (12): 1112-1114, 2008.
Article in Chinese | WPRIM | ID: wpr-292442

ABSTRACT

<p><b>OBJECTIVE</b>To detect the level of fasting plasma homocysteine (Hcy) in patients with oligospermia and/or asthenospermia and to investigate its clinical significance.</p><p><b>METHODS</b>Semen quality analyses and fasting plasma Hcy determination were performed for 86 infertility patients (21 with oligospermia, 32 with asthenospermia and 33 with oligo-asthenospermia) and 19 normal fertile volunteers. The results were compared.</p><p><b>RESULTS</b>The level of plasma Hcy was significantly higher in the infertility patients than in the normal controls (P < 0.05) and negatively correlated with sperm concentration (r = -0.433, P < 0.01), the percentage of grade a sperm (r = -0.303, P < 0.05) and the percentage of grade a+b sperm (r = -0.339, P < 0.01).</p><p><b>CONCLUSION</b>The increased level of human plasma Hcy directly or indirectly affects spermatogenesis and correlates negatively with oligospermia and/or asthenospermia.</p>


Subject(s)
Adult , Humans , Male , Asthenozoospermia , Blood , Case-Control Studies , Homocysteine , Blood , Oligospermia , Blood , Sperm Count , Sperm Motility
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