ABSTRACT
To evaluate the value of Doppler tissue imaging(DTI) to assess left ventricular systolic and diastolic function by determining motion frequency of the mitral annulus in acute myocardial ischemia and myocardial infarction. The left anterior descending coronary artery(LAD) was ligated in 10 pigs and systolic motion velocity(Sa), early diastolic velocity(Ea), late diastolic velocity(Aa) and Ea/Aa of lateral mitral annulus in apical 4 chamber view using DTI velocity model before and after ligation of LAD were determined.The results were compared with routine Doppler. In basal state, Ea/Aa was positively correlated with VE/VA (the ratio of early and late diastolic velocity of mitral flow) with Doppler imaging (?=0.82). After the ligation of LAD, Sa, Ea and Ea/Aa significantly decreased, while there was no difference in Aa. DTI is simple and easy for determining mitral annulus motion. It is a new quantitative and non invasive method to evaluate left ventricular function. [HS(2*2/3]