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Medwave ; 20(7): e7996, 2020.
Article in English, Spanish | LILACS | ID: biblio-1122647

ABSTRACT

Se sabe que la amiodarona, un potente antiarrítmico, causa toxicidad pulmonar. La neumonitis intersticial crónica es la presentación más común. Sin embargo, la toxicidad pulmonar aguda es rara y provoca una mayor mortalidad. Se presenta un paciente de 61 años con fibrilación auricular persistente que, tras tratamiento por un mes con amiodarona vía oral a dosis baja de impregnación de 400 miligramos al día, desarrolló toxicidad pulmonar aguda secundaria al antiarrítmico confirmada por radiografía y tomografía. Su caso tuvo resolución después de la suspensión del fármaco y tratamiento con esteroides.


Amiodarone, considered a potent antiarrhythmic, is known to cause pulmonary toxicity. Chronic interstitial pneumonitis is the most common presentation. However, acute pulmonary toxicity is rare and has a higher case fatality rate. We present a 61-year-old patient with persistent atrial fibrillation who, after a one-month treatment with oral amiodarone at a low dose impregnation of 400 mg/day, develops acute pulmonary toxicity, with radiographic and tomographic resolution after antiarrhythmic suspension and steroid treatment.


Subject(s)
Humans , Male , Middle Aged , Amiodarone/adverse effects , Lung Diseases/chemically induced , Anti-Arrhythmia Agents/adverse effects , Atrial Fibrillation/drug therapy , Acute Disease , Dose-Response Relationship, Drug , Amiodarone/administration & dosage , Anti-Arrhythmia Agents/administration & dosage
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