ABSTRACT
Fasciola infection [fascioliasis] appeared to be endemic in Egypt. Stool samples of fourty eight patients were coprologically diagnosed. According to Fasciola egg counting per gram stool, the severity of infection was divided into light infection in 60.5%, moderate in 27.1% and severe infection in 12.5%. No significant correlation was detected between severity of infection, and patients' sex. Complete blood picture, reticylocytic count, serum iron, immunological assays as anti-nuclear, anti- smooth muscle antibody, anti-mitochondrial anti-body, anti- DNA tests and rheumatoid factor and occult blood in stool were investigated. Normocytic normochromic anaemia was detected in 62.5% of the fascioliasis patients, microcytic hypochromic anaemia in 3 1.3% and macrocytic one in 6.3%. Highly significant negative correlation [R = -0.68] was detected between haemoglobin concentration and egg count per gram faeces. Human fascioliasis was associated with normocytic normochromic anaemia and to a lesser extent microcytic hypochromic anemia