In vitro cytotoxicity assays of extracts from some mediterranean sea algae

A cytotoxicity screening study was carried out on the ethanolic extracts of 25 species of algae collected offshore of Alexandria. The assays were performed on two proliferating mouse cell lines, a normal fibroblast line [NIH3T3] and a virus-transformed [ras] line [KA31T]. Only one extract exhibited substantial cytotoxic activity arbitrarily defined by IC50 of 10 mug/ml or less in both cell lines. Two other extracts exhibited potent activities with NIH3T3 cell line and moderate cytotoxic activities with KA31T cell line

Biological and photochemical evaluation of plants: II In vitro cytotoxicity assays of extracts from twenty three Yemeni plants

Twenty-three ethanolic extracts of unselected higher plants, grown in Yemen, were screened for their possible cytotoxic activities. Cytotoxicity assays were performed on the two proliferating mouse cell lines, NIH3T3 and KA31T. Two out of the 23 extracts exhibited potent cytotoxic activities as arbitrarily defined by IC50 of 10 mug/ml or less in both cell lines

Biological and Phytochemical evaluation of plants: l-in-vitro cytotoxicity assays of extracts from fifty Egyptian plants

A cytotoxicity screening study was carried out on the ethanolic extracts of 50 unselected higher plants growing in Egypt. The assays were performed on 2 proliferating mouse cell lines, a normal fibroblast line [NIH3T3] and a virus-transformed [ras] line [KA31T]. 10% of the examined extracts exhibited substantial cytotoxic activity arbitrarily defined by LC50 of 10 mug/ml or less in both cell lines