ABSTRACT
Abstract Introductions: Surgical Site Infection [SSI] is the most commonly reported nosocomial infection among hospital surgical inpatients. Determining measurable perioperative factors for SSI may provide information on reducing complications and improving outcome
Objective: Assess the predictive risk factors of tissue and wound complications in open colorectal operation patients
Materials and Methods: We studied 186 consecutive patients who underwent elective colorectal operation [due to pathologies such as colon cancer, inflammatory bowel disease, familial adenomatous polyposis and so on] in a cohort study between February 2004 and September 2006 in a tertiary hospital. The main outcome of surgical site infection included incision or organ/space. Multivariate analysis was performed to assess the independent association of every factor with SSI. Also odds ratio [OR] with 95% confidence interval were reported
Results: The mean age of patients was 49.4 +/- 16.5 year, and 50.5% were females. The most common preoperative diagnoses included colorectal cancer [84.9%] and familial adenomatous polyposis [10.7%]. Eighteen [9.7%] of patients suffered SSI. Of measured variables, mechanical preparation with an OR=0.053 and p value=0.002, smoking [OR=29.422 and p value=0.011], type of wound [OR=12.87 and p value=0.01], operation time [OR=3.14 and p value=0.001] and colostomy [OR=12.42 and p value=0.019] independently predicted SSI
Conclusions: The incidence of SSI in patients who underwent elective colorectal operation in present study could conform to results of the previous studies literature. Perioperative mechanical preparation, smoking, type of wound, operation time and colostomy independently predicted