ABSTRACT
Dysmenorrhea is a painful menstruation, usually cramping in nature and centered in the lower abdomen. About 60% of menstruating adolescence were reported to have some degrees of dysmenorrhea and 14% regualry missed school. This semi-experimental single-blinded study was conducted to compare the effects of fennel and mefenamic acid on the severity of pain in primary dismenorrhea. The assessment was performed on 110 volunteers at high school age [Kerman province 1381]. Samples were categorized into two groups which received either fennel or mefenamic acid. Regarding the age of menarch and beginning of dysmenorrhea, there was no significant statistical difference between these two groups. The number of cases who were compeletely or partially cured, were 44 [80%] and 40 [73%] in fennel and mefenamic acid groups, respectively. At the end of the treatment, 44 subjects [80%] in fennel group and 34[62%] subjects in mefenamic acid group needed no rest. Totally, there was no significant statistical difference between these two groups. However, due to safety of herbal drugs, chemical agents can be replaced with herbal drugs