ABSTRACT
Background: exposure to electromagnetic radiation may impair memory. This study was conducted to evaluate the effect of radiofrequency wave [hereafter referred to as RFW] on passive avoidance learning and memory in healthy males and females
Materials and Methods: ten adult male and ten female Sprague- Dawley rats [230 +/- 20 gr] were randomly divided into four groups including two control groups [one for males and one for females], and two experimental groups [exposed to 900 MHz radio frequency wave] each representing one gender. The exposure was performed for 30 consecutive days [4h/day]. Evaluation of learning and memory of the rats started on the last day of exposure by shuttle box. Learning and memory of animals was recorded by the period of time they remained within the light area; this time was called the light time
Results: results of the study showed that exposure to RFW significantly decreased the duration of light time in the rats within the experimental groups as compared to the control groups [P<0.05]. Exposure to RFW significantly decreased the light time in females in comparison to males in the experimental group [P<0.05]. Histological study of brain section did not show significant changes between Groups
Conclusion: with regard to these findings, it was concluded that exposure to RFW causes disorder in memory retention of passive avoidance learning in rats. The extent of damage to the learning and memory in rats exposed to RFW was more for females than males
ABSTRACT
Medicinal plants are valuable natural resources that are nowadays known as safe pre-materials for drug industries in the advanced countries. Black caraway is one of the most important and economical medicinal plants that can be grown naturally in some regions of Yazd province. The essence of the plant are used in treatment of diarrhea, dyspepsia, fever, flatulence, stomachache, hemorrhoids, hiccoughs, as an antihistaminic and more numerous uses in medicine industries. This plant shows several therapeutic effects on digestive and urinary tract disorders and is well known as an anti-convulsant, anthelmintic, anti-asthma and antidyspnic drug in Iranian traditional medicine. Bunium Persicum oil is capable of suppressing the initial stage of an inflammatory process. Also, this plant is used for culinary purposes and for flavoring foods and beverages. In this research, the fractionization of seed essence was done by GC method and the compounds were recognized. The DPPH test was used for estimating anti oxidant effects and the Follin-Ciocalteu method was used for estimating quantity of phenol compounds. The results revealed that- gammaTerpinene had the highest percentage in the essence of the native black caraway of Yazd province. Also, the antioxidant test showed the high antioxidant effect of the native black caraway of Yazd province with an IC50 of 2.85 microg.mg-1 and the phenolic component percentage of 117.09mg.g1. This result was much higher than previous similar studies about black caraway