ABSTRACT
Background and aim: Due to significant role of air pollutants on lung diseases this study aimed to examine the effects of concentration of air pollutants [CO¡SO[2]¡NO[2]] on Spirometric lung function
Methods: The sample cities, Arak [as an industrial contaminated city] and Khomain, [as a non-contaminated non-industrial city], were divided into Ira 10 and 5 regions, respectively. A sample of air pollutants [CO¡SO[2]¡NO[2]] was measured randomly by PSI [Pollution Standard Index] machine throughout the year from spring to winter. Random samples consisted of 522 non-smokers from Khomain and 547 from Arak were selected. Pulmonary function tests were completed on all participants. The mean concentration of air pollutants and distribution index of lung capacity were subjected to regression analysis
Results: Analysis of the results showed that PSI in Arak was 101.83+/-4.54 and in Khomain was 89.17+/-18.58 [P<0.05]. Measured values FVC and PEF in Arak were significant lower than Khomain [P<0.05]. The mean values for the concentration of CO, SO[2] and NO[2] in Arak were higher than Khomain, although the differences were significant only for CO and SO[2] [P<0.001]. The three pollutants [NO[2], SO[2] and CO] showed a significant correlation between mean VC [P<0. 001] FVC, [P<0.05] with concentrations of SO[2] and PEF with NO[2] [P<0.001]. In Arak, the correlation between the predicted FVC and concentration of CO was negative and significant
Conclusion: The mean value of concentration of SO[2], CO and NO[2] in Arak were higher than Khomain. In Arak, a significant negative correlation was also observed between FVC and the concentration of CO. These pollutants and their resources should be annually measured and monitored