ABSTRACT
There are various kinds of cutaneous manifestations in the end stage renal disease [ESRD] which may present or associate with it. The goal of this study has evaluated cutaneous manifestations of patients with chronic renal failure on hemodialysis. In a descriptive study from April to September of 2002 cutaneous signs and symptoms of patients with ESRD who were being dialyzed in three referral hospital in Mashhad were recorded. Serum levels of PTH, Ca, P were determined and correlation of them with pruritus were studied. Data collected by questionnaire and analyzed by descriptive statistics. Eighty-two patients with ESRD were admitted in this period of which 12 cases were excluded during the study and 70 completed it. The most common symptom was pruritus in 70% of cases. Signs include dryness of skin in 50%, skin color change in 71/5%, and half and half nail in 30%. Serum PTH level in patients with pruritus was higher than patients without pruritus [P=0.01] but there were not any significant difference in serum Calcium and phosphorus levels in two groups [P> 0.05]. Although the frequency of cutaneous manifestations in ESRD were similar but in few instance our results were not similar to the western countries. Factors such as race, climates, socioeconomic state... may have some role in these difference