ABSTRACT
A survey of occurrence of Salmonella in blood and bone marrow cultures was conducted in 1989- 1990 and 1999- 2000 [Sina hospital, Kermanshah]. A total of 496 [12.3%] and 60 [2.4%] Salmonella strains were isolated [from 4020 and 2447 cultures]. In 1989- 1990, the isolated strains were: S. typhi 448 [98.5%], S. paratyphi A 40 [8%], S. paratyphi B 5 [1%] and S. paratyphi C 3 [0.5%]. In 1999- 2000, the isolated strains were S. typhi 59 [98%] and S. paratyphi B 1 [1.5%]. There was a 60.9% reduction in the number of specimens over the 2 periods. The rate of Salmonella isolation fell from 12.3% [1989- 1990] to 2.4% [1999- 2000]. There was a 10.2, 8.3 and 6.6 times increase in resistance of S. typhi strains to ampicillin, chloramphenicol and trimethoprim- sulfamethoxazole respectively