Bladder cancer in the three main age groups

Despite of the fact that the incidence of carcinoma of the urinary bladder associated with bilharziasis that occurs at young age compared to non-bilharzial type, the incidence of this tumor in young adults was not high. On the other hand, over 70- years the incidence was three times greater than below the age of 40 years. A retrospective survey of bladder cancer cases during six years from September 1987 to September 1993 showed 18.2% incidence. The two groups of extreme age were analyzed [below 40 years and 70 years and above] and compared with middle age group. Out of the twenty four cases aged below 40 years [4.8%], only 4 patients [0.8%] was classified histologically as transitional cell carcinoma [T.C.C.]. Out of the 90 patients, presented over 70 years of age [18.1%], 45 showed TCC [9%] on histopathological examination, compared to 35.7% in the middle age group

Treatment of lead poisoning by S-adenosyl-L-methionine

Lead poisoning remains a major public health problem. It induces many biochemical and histopathological changes that affect many organs. The effect of S-Adenosyl-L-Methionine [SAMe] administration on the management of lead toxicity was investigated. Rats with either acute or chronic lead intoxication were treated with S.C. injection of SAMe [30 mg/kg body weight] daily over a period of 2 days. The beneficial effects of SAMe were evaluated by a comparison between the treated and non-treated animals using different biochemical and histopathological paramenters. Results obtained from both acute and chronic poisoning were in similar pattern