ABSTRACT
This study was conducted to evaluate the clinical and reproductive outcomes after Laparoscopic Ovarian Drilling [LOD] performance in infertile women with Clomiphene resistant Poly Cystic Ovary Syndrome [PCOS]. Regular menstrual cycles, ovulation and pregnancy rates have been considered as three main outcomes being evaluated in this study. 72 Clomiphene-resistant anovulatory women with PCOS in Karaj Hospital were taken into account in this study from 2002-2005. Laparoscopic Ovarian Drilling [LOD] using a needle cautery was performed. Each ovary was punctured at 6 points. Patients were followed for 24 months for evaluating the outcome. After laparoscopy, regular menstruation occurred spontaneously in 82.6% and maintained regular at least for 6 months. The incidence of conception at 6, 12, 18, and 24 months after surgery was 14.7%, 36.8%, 58.5%, 67.6% respectively. Laparoscopic ovarian drilling is an effective treatment in Clomiphene-resistant anovulatory women with PCOS