ABSTRACT
Infertility is a complex crisis in couple's life and can produce severe psychological pressure on both partners. Depression, stress, low self-esteem, and marital sexual dissatisfaction are among the psychological outcomes of infertility. This study was aimed to determine the relation between infertility and sexual satisfaction. This was a cross sectional study in which depression and sexual satisfaction rate among 150 infertile versus 150 fertile couples [in Tabriz- in 2005] were investigated and further analyzed. Random Sampling was used to select study population. Data gathering was performed using a questionnaire consisting of 2 parts including a section on demographic characteristics, and also a Larson standard questionnaire for determining sexual Satisfaction]. Data were analyzed using descriptive statistical methods, independent t-test, and >2. Findings: There was no significant difference associated with mean sexual satisfaction rate between infertile and fertile men and infertile and fertile women [p=0.707, t=0.377 in men; p=0.370, t=0.898 in women]. However, a statically significant relationship between sexual satisfaction score and duration of marriage, income status, number of unsuccessful treatment, length of time when infertility diagnosed, and performance of diagnostic tests was found. Considering the unpleasant effects of sexual dissatisfaction on physical and emotional health and also the occurrence of infertility-originated divorce, attempt has to be made for early diagnosis and treatment of undesirable situation in both partners
ABSTRACT
Half of the world's population is infected with helicobacter pylori. This organism is one of the main causes of peptic ulcer disease, gastritis and gastric cancer. This infection is most frequently acquired in childhood. There is strong evidence that eradication of infection improves healing and reduces the risk of recurrence and rebleeding in patients with duodenal or gastric ulcer. There is no consensus as to treat infected children without ulcer. The aim of this study was to compare the efficacy of two therapeutic regimens in eradication of infection in children. This study was a double-blind randomized clinical trial conducted in Tabriz Children Hospital. A total of seventy children aged 4 to 15 years were studied. These patients were referred to Endoscopy Unit and upper endoscopy and biopsy were performed. They were positive for helicobacter pylori by histological confirmation. The patients were randomly enrolled in two therapeutic groups: group-A[n=41] received omeprazole as a proton pump inhibitor, amoxicillin and metronidazole [PAM] and group-B [n=36] received omeprazole, amoxicillin and clarithromycin [PAC]. The duration of treatment was two weeks in both groups. To confirm eradication, UBT was performed after 8 weeks of treatment. Data were analyzed using SPSS package version 15. P-value <0.05 was considered significant. Mean age in PAM and PAC groups were 8.8 +/- 2.5 and 9.6 +/- 2.9 years, respectively. The age difference was not statistically significant [P=0.24]. The most common initial symptom was chronic abdominal pain in both PAM and PAC groups [81.3% and 76.3%, respectively]. There was no statistical difference in frequency of initial symptom between the two groups [P=0.41]. Side effects during treatment were seen in both PAM and PAC groups [23.7% and 19.7%, respectively]. Most patients in both groups experienced symptoms improvement after treatment whether complete or partial. In PAM and PAC groups, symptoms improvement was seen in 92.1% and 91.2%, respectively. There was no significant statistical difference between the two groups [P=0.64]. The intention to treat analysis in PAC and PAM groups were 75%and 73%, respectively and per-protocol analyses were 87% and 78.9%, respectively. There was no statistical difference in helicobacter pylori eradication rates between the two groups [P=0.39]. Our study suggested that both PAM and PAC regimens are effective in eradication of infection. Eradication of infection also can cause significant improvement of initial symptoms