[ survey of age at natural menopause according to determinants factors in Arak city in 2007]

Menopause is a natural period of life. It means the permanent cessation of menstruation and the end of reproductive period which occurs between 45-52 years old. It also serves as an indicator of population health as the occurrence of menopause indicates the increased risk for the onset of several chronic diseases. In this study, the mean age of natural menopause among women in Arak [Central Iran] was investigated, considering their reproductive and socio-economic-demographic factors and their health behaviors. This study was an observational cross-sectional study on a population base, carried out in 2007 year. Interviews and questionnaires were used for gathering data from 458 women resident in Arak city, who had undergone a natural menopause. Sampling was multistaged using postal zones and selecting samples in each zone. Data was analyzed using variance analysis, multiple regression, T and correlation coefficient tests. Findings showed that the mean age of menopause in our sample was 48.2 +/- 2.34 years [95% CI: 47.98- 48.41] and its median was 49 years. The mean age of menopause in women who were never married was less than married women [P= 0.015]. Low income level [P= 0.003], having physical activity [P= 0.004], number of pregnancies [P<0.001], age of last pregnancy [P=0.026] and place of birth [P=0.003] were meaningfull factors in age of menopause. This phenomenon must be documented in Iran because of its strong link with mortality and morbidity of the growing number of women who are reaching advanced ages; whose one forth of life is after menopause. Therefore health education as the best way for changing their lifestyle is suggested

[ case report of testicular feminization syndrome]

Testicular feminization syndrome is a disorder with the prevalence of 1 in 20000 to 64000 male birth. It's characteristics are female phenotype, male caryotype [64XY] and normal to increased testosterone and LH levels. In this article a case testicular feminization is reported. The patient was a 16 years-old woman with primary amenorrhea and without secondary sexual characteristics. The patient had normal female external genitalia, absent axillary and pubic hair, immature breast, and repaired bilateral inguinal hernia with pathology report of immature testicular tissue. FSH and LH levels were elevated. Testosterone level was normal. Sonography and CT scan of pelvis did not show uterus and adnex. Karyotype was 46XY. It is recommended that due to the risk of neoplasia, the existing testes must be removed. Also hormone therapy must be done for the patients