ABSTRACT
Momordica Charantia [MC] belongs to the cucurbitaceae family. MC is A plan that is widely used in traditional medicine as an antidiabetie agent.The aim of the present study was to evaluate the effect of the raw fruit of MC on some blood biochemical parameters in rats. Three groups of rats received a diet containing 1%, 2% and on MC [control group] respectively for a duration of two months. Blood samples were collected in the begining and at the end of the study. The sera were separated and used for determining of biochemical parameters including fasting blood suger [FBS]. glycated hemoglobin [HbAlc], cholesterol [cho], high density lipoproteins [HDL], low density lipoproteins [LDL], triglycerides [TG], urea [U] and creatininc [C]. The diet containing 1% and 2% MC decreased FBS significantly [p<0.002], and HbAlc [p<0.004] as compared to the control group. The 2% MC diet decreased Cho [p<0.001] and LDI [p<0.001] as compared to the control group. There was no significant change in the other factors. On the basis of the results obtained, it may be concluded that MC can effectively normalize glucose and lipid in patients. For better conclusion experimental human studies are recommended
ABSTRACT
The frequency of methicillin-resistant Staphylococcus aureus [MRSA] was determined in 526 bacteria isolates from the infected sites of patients with staphylococcal infection, and from the nose or throat of healthy carriers among hospitalized patients, hospital personnel and the control group not in contact with hospitalized patients. Total number of the resistant isolates [or with immediate response] to 1micro g oxacillin was 9.9% and considered as MRSA. Vancomycin and trimethoprim-sulfamethoxazole were the most active antibacterial agents against all the bacterial isolates [p<0.001], followed by erythromycin [93.5%], and gentamicin [93.3%]. Sensitivity to penicillin, ampicillin and amoxicillin was very low [less than 4%]. The rate of MRSA and antibacterial resistance was higher in the S. aureus isolated from clinical infection [25%], compared with those from carriers [7.9%] p<0.001. Among the bacteria isolated from carriers, throat samples showed a higher rate of resistance to antimicrobial agents and a higher rate of MRSA [13.3%] compared to those isolated from the nose [5.2%], p<0.002