[Evaluation of the antibacterial activity of quercus persica jaub and spach fruit's hidroalcoholic extract in disc diffusion method]

As a result of indiscriminate use of antimicrobial drugs in the treatment of infectious diseases, microorganisms have developed resisrtance to many antibiotics and there is a need to develop antimicrobial drugs. One approach is use of local medicinal plants which represent a rich source of novel antimicrobial agents. Due to rapid increase of antibiotics resistance, fewer side effects of chemical drugs, antibacterial properties of oaks and other reasons, this study was carried out. In this study the antibacterial activity of hidroalcoholic extract of oak fruit was evaluated and compared with some in-use antibiotics. Milled oak fruit that their hull was separated was extracted with water+ethanol in Soxhlet's apparatus .The effect of extract in three concentration [25, 50, 75 mg/ml] were tested using agar diffusion method on Staphylococcus aureus ATCC 25923, Staphylococcus epidermidis RTCC 1898 and Escherichia coli O157: H7. Results showed that the effect of the extract on bacteria was concentration-dependent. In compared with antibiotics, the effect of 75 mg/ml concentration of extract on S. aureus was similar to GM, lesser than K and higher than TOB. Also this concentration of extract had a similar effect to K, higher than GM and lesser than TOB on S. epidermidis. This effect on E. coli was lesser than GM and K, but in compared with TOB was higher. results show that Quercus persica J. and Sp. possesses compounds with antibacterial properties

In vitro screening for antioxidant activity and cancer suppressive effect of blackberry [Morus nigra]

Anthocyanins are natural pigments widely spread in nature. Anthocyanin color molecules are a subclass of flavonoids. They are responsible for red, purple, and blue colors of many flowers, fruits and vegetables. Fruits and berries are sample sources of anthocyanins in nature. In many researches, the positive effects of fruits and berries intake on human health have been reported. Anthocyanins are considered to contribute to the healthiness of fruits and berries for their antioxidant, anti-carcinogenic, anti-inflammatory, and anti-angiogenic properties. The aim of the present study was to investigate the scavenging capacities towards super oxide anion radicals, and nitrite radicals and reducing power of anthocyanins extracted from Blackberry [Morus nigra] as a potential source of natural functional substances for use as dietary antioxidants. For superoxide anion radical assay, the superoxide anion radicals were generated by a pyrogallol auto oxidation system, Nitric oxide radical inhibition was done by using Griess Illosvoy reaction and its reducing power was determined according to the Oyaizu method. At least, all samples showed a potential antioxidant capacity that increased proportionate to the concentration of extracts. In this study, anthocyanin pigment was extracted from Blackberry by soaking and wetting in ethanol [1% acidified]