[Survival and causes of mortality of cirrhotic patients in Tunisian center a study of 114 patients]

The aim of this study is to determine the survival and the principal causes of death in our cirrhotic patients in whom the B and C viral infection represented the principal causes. It's a retrospective studs that includes 114 cirrhotic patients hospitalized between 2000 and 2005 in the department of hepato-gastro-enterology of sahloul. The mean age was of 53 years with extremes of 15 to 85 years; 65 were men 57%] and 49 were women [43%]. After a follow-up of 29, 4 months, 51 patients died [44, 7%]. The causes of death were hepatocellular carcinoma in 19 cases [16, 7%], hepatorenal syndrome in 17 cases [14, 9%], hepatic encephalopathy in 12 cases [10, 5%], infection of ascitis in I case and upper digestive hemorrhage in 2 cases [1, 8%]. The global survival of patients was 66%for 2 years and 47%for 5 years. The survival for 5 years of viral B cirrhosis was 34%, but it was 51%in non B viral cirrhosis but the difference was not statistically significant [p=0, 6]. The cirrhotic patients have a premature mortality in comparison to the general population. The hepatocellular carcinoma remains one of the principal causes of death, where the interest of early screening for degeneration

[Prevalence of celiac disease in patients with type 1 diabetes mellitus]

The aim of our study was to determine the prevalence of celiac disease in patients with type 1 diabetes mellitus. Between january 2004 and december 2005, 72 patients with type I diabetes mellitus and having pseudo ulcerous dyspepsia were included in this prospective study. Upper gastrointestinal endoscopy with proximal intestinal biopsies was performed in all patients. Patients with villous atrophy were tested for anti-gliadine antibodies, anti-endomysium antibodies and for anti-human tissue transglutaminase antibodies. Villous atrophy was observed in three patients [4, 1%]. It was subtotal in two cases and total in one case. Anti-gliadine antibodies, anti-endomysium antibodies and anti-human tissue transglutaminase antibodies were positive to three patients. The prevalence of celiac disease in patients with type 1 diabetes mellitus is high [4, 1%]. Early screening of celiac disease must be recommended to this diabetic population