ABSTRACT
Acute blood complications form the most frequent and important reactions among the blood transfusion adverse effects; acute hemolytic reaction, bacterial contamination, and transfusion related acute lung injury [TRALI] are the most frequent causes of death following blood transfusion. In this descriptive prospective study, 2633 patients hospitalized in surgical and non-surgical departments of 11 hospitals having received blood transfusion were evaluated for acute blood transfusion reactions. Among these patients, 20 [0.8%] encountered acute blood transfusion reactions. Out of this group of patients, eight experienced febrile non-hemolytic transfusion reactions, nine had allergic reactions, one developed blood group incompatibility, and two disseminated intravascular coagulation [DIC]. This study indicates that the most prevalent blood transfusion reactions were fever and allergy [0.3%]. This reported rate [0.5-6%] is lower than the global rate. The rate of blood group incompatibility in this study was 0.03%, showing a higher prevalence than the global rate [0.004%]