Chemical, biological and organoleptic evaluation of newly formulated therapeutic diets for protein calorie malnutrition

Three supplementary food mixtures high in protein and calories were prepared using different percentage of locally produced cereals and legumes in addition to 10% skimmed milk powder in each formula to be used as therapeutic diets for infants suffering from protein energy malnutrition. These prepared mixtures were undergone chemical, biological and organoleptic evaluation. The data obtained revealed that 100g of each mixture provided 38, 28 and 20 g. protein and 382, 366 and 364 calories in formulae I, II and III respectively. The biological evaluation was carried out in comparison to three locally available food mixtures [Creacon, Gerber and Riri] comparable in protein percentage and casein containing diet as a control group using experimental rats. The data obtained showed that body weight gain increased significantly only in case of rats fed creacon and formula II. The food and protein efficiency ratios for formulae I and II were higher compared to the control which was significant for formula II. Organoleptic evaluation revealed that formula I scored as very good, then comes formula II then at last formula II which were both scored as good

Skin diseases and enzymatic antioxidant activity among workers exposed to pesticides

In this study, 150 workers exposed to pesticides and 50 healthy control subjects were given clinical and dermatological examinations, patch tests, tests of liver and renal function, complete blood count, blood sugar and urinalysis. Activity of the antioxidant enzymes superoxide dismutase, glutathione peroxidase and glutathione reductase was also evaluated. Dermatological findings were positive in 78%, 76% and 54% of workers exposed to organophosphates, pyrethroids and carbamate pesticides respectively. The patch test was positive in 70% of workers exposed to pyrethroids and 64% exposed to carbamate pesticides. Liver enzyme levels were generally increased in workers while antioxidant enzyme activity was significantly decreased in all workers compared with the controls

Some Biochemical and nutritional changes in relation to aspirin adminstration with different carbohydrate dets

The effect of aspirin administration with different carbohydrate diets, on plasma lipids proteins and glucose, as well as nutritional parameters, was studied in rats. The results showed that feeding balanced diet during aspirin administration produced no changes on different plasma parameters. Feeding high sucrose diet with high dose of aspirin produced significant increase of total lipids and decrease of high density lipoprotein cholesterol [HDL-ch]. Giving the high dose of aspirin during feeding high starch diet, produced significant decrease of HDL-ch and its ratio to total cholesterol. Plasma total protein and globulin increased significantly. Concentrating the nutritional parameters, low dose of aspirin failed to show any significant changes either in body weight gain or food efficiency regardless of the type of the diet. On the other hand, high aspirin dose resulted in reduction of food intake, body weight gain as well as food efficiency ratio on feeding some diets