[Quantitative comparison of un-stimulated whole saliva flow rate among menopausal women and same aged men]

Menopause can be associated with psycho-somatic changes in oro-facial areas like xerostomia and Burning Mouth Syndrome, although these findings are controversial. The present study sought to compare the Un-stimulated Whole Saliva [UWS] flow rate of a group including menopausal and postmenopausal women and same-aged men. In this cross-sectional analytic-descriptive study 40 menopausal and post-menopausal women [as experimental-group] and 40 same-aged men [as control group] without any systemic diseases and any drug consumption were divided into 2 groups, xerostomia was evaluated by a questionnaire, and their psychological conditions were assessed with HAD scale. UWS flow rate was measured by the spitting method. Data were analyzed by chi-square, Krusscal Walis and Mann-Whitney tests. Mean of UWS flow rates in experimental group was significantly less than that in control group [P=0.006]; no significant difference was found between the two groups regarding psychological condition. Also, menopausal women had significantly greater xerostomia than men [45% vs 15%] [P=0.003]. Based on this study, xerostomia and reduction in UWS flow rate are sequences of menopause, these findings necessitate the increasing awareness of menopausal and postmenopausal women for controlling the methods of these problems

[Comparison of serum CA-125 level in ruptured and unruptured tubal pregnancies in Yazd/Iran during 2001-2006]

This study aimed to determine if serial measurement of serum CA-125 level could be used as a useful test in the differential diagnosis of intact and ruptured tubal pregnancies. In a single-blind prospective controlled clinical study, 59 women with tubal pregnancy of 6-12 weeks [26 women with ruptured tubal pregnancy, 33 women with intact tubal pregnancy and 59 women with normal intrauterine pregnancy of the same gestational age as control group] were studied prospectively. Serum CA-125 levels were measured in all women and compared among three groups. Demographic features [age, gestational age, parity and educational level] were not significantly different in three groups. CA-125 level in ruptured tubal pregnancy group was significantly higher than that in control group [P = 0.04]. Both these two groups had higher levels of CA-125 comparing to the intact tubal pregnancy group [P = 0.001, P = 0.006, respectively]. In intact tubal pregnancies managed with medical treatment, serial measurements of CA-125 could be a supplementary test for an early diagnosis of tubal rupture