ABSTRACT
Psychotic disorders have been observed in association with some autoimmune disorders. Moreover, autoimmune mechanisms have been recently considered in evaluation of schizophrenia spectrum disease managements. Vitiligo is one of the autoimmune diseases, but there is no report of vitiligo association with psychosis. We report three patients with vitiligo and schizophrenia spectrum disease that are indicative of the role of autoimmunity in psychosis. Moreover, unusual manifestation and poor response to treatment in the reported cases show that autoimmunity can complicate the prognosis of psychosis
Subject(s)
Humans , Psychotic Disorders , Autoimmune Diseases , SchizophreniaABSTRACT
Lycanthropy is an unusual belief or delusion in which the patient thinks that he/she has been transformed into an animal. In rare cases, the patient believes that another person has been transformed into an animal. In this case report, a patient who had an uncommon variant of lycanthropy is introduced. The patient's symptoms had appeared after consumption of ecstasy. This shows the occurrence of uncommon and rare psychosis after ecstasy drug use especially in susceptible patients to schizophrenia. Ecstasy can induce paranoid psychosis similar to schizophrenia. It seems that in the presented case, ecstasy had a role in the incidence of the underlying suceptibility of the patient to schizophrenia