ABSTRACT
Permanent pacemakers are applied to treat some 2[nd] and 3[nd] degree AV blocks. Previous studies have shown the hemodynamic changes that may occur after pacemaker implantation. In this study, we have evaluated these hemodynamic changes from a different view point, with measurement of urinary sodium and blood pressure. This is a before and after clinical trial study in which 30 patients, who were hositalized for permanent pacemaker implantation for the first time in Tehran heart center during 3 years, including 12 women [mean age 62.92 years] and 18 men [mean age 60.07 years], were tested for urinary specific gravity and sodium, blood pressure, blood sodium and potassium, before and after pacemaker implantation. Paired sample T test and Chi Square test were used for statistical analysis. Systolic blood pressure was 136.5 mmHg and 120.6 mmHg before and after pacemaker implantation, [P< 0.001]. Also, after pacemaker implantation, urinary sodium rose from 83.45 meq/L to 106.61 meq/L [p=0.018]. This study is consistent with previous studies, which showed hemodynamic changes after permanent pacemaker implantation including decrease in blood pressure and elevation of serum neuropeptides