[Evaluation of satisfaction and its factors in patients in emergency departments of Isfahan province in 2005]

Patient satisfaction is an indicator of service quality in hospitals, especially in the emergency departments. We evaluated this item and its factors in hospitals in Isfahan province in 2005. In a cross-sectional study 1372 patients in 48 emergency departments were assessed and data were collected on the basis of a questionnaire. Mean and total scores and percent of amounts of satisfaction were used. Anova and T-test were used and p < 0.05 was considered significant. 82.8 percent of patients were satisfied with services with mean score of 111.9+1- 14.8 from maximum score of 145. Care givers' speed, accuracy and behavior were domains with most score drug availability and costs took least scores. Private hospitals and those affiliated to special organizations and foundations and all university hospitals exhibited decreasing scores as 116.9, 113.6 and 109.6 respectively. Patients' educational level showed a reverse relation to satisfaction, singles were more satisfied than married. This study reveals costs and drug availability as the major causes of dissatisfaction, hence demanding more attention

[Application of radioimmunoassay technique for determination of antigen concentration in different cells with a new monoclonal antibody]

Binding a monoclonal antibody to tumor associated antigens is an effective method for cancer therapy because these agents can specifically target malignant cells, in fact monoclonal antibodies are effective agents for diagnosis, grading and treatment of different kinds of cancers. In this research, a new monoclonal antibody against colon cancer cells was prepared and antigen concentration in different cells determined by a radioimmunoassay method using iodine [I-125] labeled protein G. 125I-labeled protein G percent binding to white blood cell, HT29, LS180 and MCF7 cell lines were 7.1%, 91.2%, 75.8% and 40.2%, respectively. Regarding importance of monoclonal antibody applications, it is necessary to find an efficient method for their evaluation in cancer therapy. In this method, a radioactive agent with no count restriction was used. Also by this method, amount of the antigen can be easily quantified